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Fig. 4 | European Journal of Medical Research

Fig. 4

From: Multi-omics cluster defines the subtypes of CRC with distinct prognosis and tumor microenvironment

Fig. 4

Diversely genetic alterations among two subtypes. A The waterfall plot of the top 20 most frequently mutated genes in CS1. B The waterfall plot of the top 20 most frequently mutated genes in CS2. C Forest plot of significantly differentially mutated genes between two subtypes. D Comparison of tumor mutation burden (TMB) and transitions and transversions (TiTv) among two subtypes. E Bar plot of fraction genome altered among two subtypes. F The copy number amplifications and deletions among the 22 chromosomes in CS1. G The copy number amplifications and deletions among the 22 chromosomes in CS2. H The heatmap shows the mutually co-occurring and exclusive mutations of the top 20 frequently mutated genes

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