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Table 3 Reproductive Characteristics of Female PAH Patients

From: Estrogen exposure, obesity and thyroid disease in women with severe pulmonary hypertension

 

Premenopausal

Postmenopausal

No. of subjects

42

36

BMI > 30 kg/m2

22

22

History of fewer than 8 periods/year

12

9

History of infertility

6

0

   history of acne

3

3

   history of excess hair

3

6

   history of PCOS

1

2

Years of Menstruation

  

   < 15

3

0

   15-29

30

12

   30-35

6

7

   > 35

3

17

Menopause status

  

   Natural menopause

 

17

   Induced menopause

 

19

Oopherectomy

 

8

Parity

  

   Parous

37

30

   Nulliparous

5

6

No. of births

  

   1

3

5

   2

22

14

   3

8

6

   4

4

3

   5

0

2

Use of exogenous female hormones

  

   Never

13

2

   Past

29

34

Oral contraceptive pills

29

33

Depo-Provera

2

1

HRT (oral)

 

24

HRT (transdermal)

 

2

Vaginal estrogen cream

 

1

   Current

  

Oral contraceptive pills

1

 

HRT (oral)

 

3

Hormone use (years)

  

   > 10

19

20

   > 15

1

2

   > 20

2

7

Use of SERMs (EVISTA)

 

2

History of IUD

3

9

History of breast cancer

0

6

   Use of tamoxifen

 

6

History of ovarian cancer

0

1

History of breastfeeding

7

26

   > 24 months

 

10

History of DVT

0

3