Effect of intracerebroventricular injection of interleukin-1-beta on the ventilatory response to hyperoxic hypercapnia

Table 2 Ventilatory and breathing pattern responses to hypercapnia before and after intracerebro-ventricular injections of IL-1β.

Parameters	Interleukin-1β
	Before	After
Slop of ventilatory response, ml/min/mmHg	5.5 ± 0.5	2.9 ± 0.3**
Slop of tidal volume response, ml/mmHg	0.05 ± 0.005	0.03 ± 0.003*
Slop of mean inspiratory flow response, ml/s/mmHg	0.2 ± 0.02	0.1 ± 0.01**
Slop of esophageal pressure response, mmH₂O/mmHg	0.1 ± 0.02	0.1 ± 0.04

Values are means ± SE. *P < 0.05 and **P < 0.01 for the comparison before and IL-1β treatment.

ISSN: 2047-783X