RETRACTED ARTICLE: Effects of uric acid on endothelial dysfunction in early chronic kidney disease and its mechanisms

Table 5 Correlation between serum UA, NO, ET-1, and NO/ET-1 ratio as well as P _CIPA , SOD, MDA, CRP, ox-LDL, and LDL

	Serum uric acid (μmol/L)		Serum NO (μmol/L)		Serum ET-1 (pg/mL)		NO/ET-1 ratio		P_CIPA(%)
	r value	P value	r value	P value	r value	P value	r value	P value	r value	P value
SOD (U/mL)	−0.6885	0.0277	0.8179	0.0038	−0.7793	0.0079	0.8143	0.0041	−0.8180	0.0000
MDA (nmol/mL)	0.8195	0.0037	−0.9171	0.0002	0.8658	0.0012	−0.9143	0.0002	0.8015	0.0053
CRP (μg/mL)	0.7251	0.0177	−0.7554	0.0115	0.7447	0.0135	−0.8042	0.0050	0.6752	0.0322
ox-LDL (mmol/L)	0.8479	0.0019	−0.7459	0.0132	0.7900	0.0065	−0.7949	0.0060	0.5266	0.1179
LDL (mmol/L)	0.6356	0.0483	−0.5080	0.1339	0.5734	0.0831	−0.4947	0.1460	0.5902	0.0725

Note: NO as dependent variable and SOD, MDA, CRP, ox-LDL, LDL as independent variables, multiple stepwise regression analysis showed that serum SOD and CRP entered the equation, and the equation was y = 0.315 × ₁-0.802 × ₂-22.120 (y = NO, ×₁ = SOD, ×₂ = CRP; -22.120 was a constant). ET-1 as dependent variable and SOD, MDA, CRP, ox-LDL, and LDL as independent variables, multiple stepwise regression analysis showed that serum ox-LDL and SOD entered the equation, and the equation was y = 0.051 × ₁-0.082 × ₂ + 22.517 (y = ET-1, ×₁ = ox-LDL, ×₂ = SOD; 22.517 was a constant). NO/ET-1 ratio as dependent variable and SOD, MDA, CRP, ox-LDL, LDL as independent variables, multiple stepwise regression analysis showed that serum SOD and CRP entered the equation, and the equation was y = 0.102 × ₁-0.316 × ₂-13.151 (y = NO/ET-1 ratio, ×₁ = SOD, ×₂ = CRP; 13.151 was a constant). P_CIPA as dependent variable and SOD, MDA, CRP, ox-LDL, LDL as independent variables, multiple stepwise regression analysis showed that serum SOD entered the equation, and the equation was y = 111.437-0.397 × ₁ (y = P_CIPA, ×₁ = SOD; 111.437 was a constant).

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