Figure 1From: Clinical implications of the quantitative detection of ID4 gene methylation in myelodysplastic syndrome Methylation frequency of CpG sites and association between the ID4 methylation percentage. (A) Methylation frequency of CpG sites in the ID4 gene in NBM, MDS and MDS-AL. Filled circle and empty circle represent one methylated CpG site (CG) and unmethylated CpG site (TG), respectively. P < 0.001. (B) Association between the ID4 methylation percentage using bisulfite sequencing PCR and methylight. Using linear regression, we obtained a goodness of fit of r 2 = 0.7168. Using an exponential curve, the goodness of fit was r 2 = 0.8485. AL, acute leukemia; MDS, myelodysplastic syndrome; NBM, normal bone marrow; TSS, transcriptional start site.Back to article page