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Table 3 Surgery related information

From: Predictive value of the Adult Comorbidity Evaluation 27 on adverse surgical outcomes and survival in elderly with advanced epithelial ovarian cancer undergoing cytoreductive surgery

Characteristic

ACE-27 low (0–1)

ACE-27 high (2–3)

p value

n = 132

n = 32

Age (median (IQR))

68 (66,70)

67 (66,71)

0.534

Type of surgery

 PDS n(%)

100 (75.75)

25 (78.12)

0.778

 NACT/IDS n(%)

31 (23.48)

7 (21.87)

 

SCS

   

  ≤ 3 n(%)

94 (71.21)

25 (78.12)

0.284

  ≥ 4 n(%)

33 (25.00)

5 (15.62)

 

 Operation time (median (IQR))

4.6 (3.5,5.3)

3.8 (2.7,4.8)

0.016

ASA

 I–II n(%)

97 (73.48)

20 (62.5)

0.218

 III–IV n(%)

35 (26.51)

12 (37.5)

 

Residual disease

   

 R0 n(%)

81 (61.36)

17 (53.12)

0.41*

 R1 n(%)

29 (21.96)

8 (25.00)

 

 R2 n(%)

9 (6.82)

4 (12.50)

 

Ascites

   

  < 1000 mL

66 (50.00)

11 (34.38)

0.033

  ≥ 1000 mL

44 (33.33)

18 (56.25)

 

 Unintended ICU admission

12 (9.09)

8 (25.00)

0.014

Perioperative complication

 II–V n(%)

39 (29.54)

15 (46.87)

0.061

 III–V n(%)

9 (6.82)

7 (21.87)

0.018*

 Grade III + complication or unintended ICU admission n(%)

16 (12.12)

11 (34.37)

0.002

Intraoperative blood loss

  ≤ 0.5L n(%)

66 (50.00)

20 (62.50)

0.442

 0.5 ~ 1L n(%)

40 (30.30)

7 (21.87)

 

  ≥ 1L n(%)

26 (19.69)

5 (15.62)

 

 Days to chemotherapy (median (IQR))

11 (9,19)

10 (9,27)

0.692

Cycle of chemotherapy

 No chemotherapy

15 (11.36)

5 (15.62)

0.747*

  < 6 cycles n(%)

56 (42.42)

12 (37.5)

 

  ≥ 6 cycles n(%)

60 (45.45)

13 (40.62)

 

 LOS (median (IQR))

20 (17,25)

19 (15,22)

0.323

  1. IQR, interquartile range; CRS, cytoreductive surgery; PDS, primary debulking surgery (PDS); NACT/IDS, neoadjuvant chemotherapy followed by interval debulking surgery; SCS, Mayo Surgical Complexity Score; ASA, American Society of Anesthesiologist; ICU, intensive care unit; LOS, Hospital length of stay
  2. *Fisher exact test