Table 1 Baseline characteristics of participants
eGFR group | Q1 (< 94.07) | Q2 (94.07–105.10) | Q3 (105.10–115.75) | Q4 (≥ 115.75) | P value |
|---|---|---|---|---|---|
Participants | 6133 | 6137 | 6134 | 6137 | Â |
Age (years) | 60.11 ± 13.37 | 54.36 ± 11.32 | 46.56 ± 8.92 | 35.96 ± 6.64 |  < 0.001 |
BMI (kg/m2) | 25.17 ± 3.11 | 24.94 ± 3.21 | 24.84 ± 3.26 | 24.28 ± 3.78 |  < 0.001 |
SBP (mmHg) | 132.22 ± 18.75 | 128.65 ± 17.56 | 125.50 ± 16.75 | 122.10 ± 15.40 |  < 0.001 |
DBP (mmHg) | 79.61 ± 11.46 | 79.26 ± 10.94 | 78.56 ± 10.99 | 76.00 ± 10.78 |  < 0.001 |
FPG (mmol/L) | 5.99 ± 0.33 | 5.97 ± 0.32 | 5.94 ± 0.32 | 5.89 ± 0.29 |  < 0.001 |
TC (mmol/L) | 5.10 ± 0.95 | 5.11 ± 0.96 | 4.99 ± 0.93 | 4.72 ± 0.93 |  < 0.001 |
TG (mmol/L) | 1.53 (1.07–2.24) | 1.50 (1.03–2.19) | 1.46 (0.99–2.20) | 1.20 (0.81–1.88) |  < 0.001 |
HDL-c (mmol/L) | 1.33 ± 0.29 | 1.34 ± 0.32 | 1.32 ± 0.30 | 1.32 ± 0.30 |  < 0.001 |
LDL-c (mmol/L) | 2.97 ± 0.71 | 2.98 ± 0.73 | 2.89 ± 0.71 | 2.72 ± 0.70 |  < 0.001 |
ALT (U/L) | 21.30 (16.00–30.10) | 22.00 (16.00–32.30) | 23.20 (16.00–35.00) | 22.00 (14.00–36.10) |  < 0.001 |
AST (U/L) | 25.00 (20.63–30.98) | 24.88 (20.10–30.73) | 24.50 (19.58–31.00) | 23.11 (18.00–30.00) |  < 0.001 |
BUN (mmol/L) | 5.40 ± 1.24 | 5.09 ± 1.19 | 4.88 ± 1.17 | 4.55 ± 1.11 |  < 0.001 |
Scr (umol/L) | 86.23 ± 13.41 | 73.19 ± 12.17 | 68.21 ± 11.81 | 62.33 ± 11.28 |  < 0.001 |
eGFR (mL/min·1.73 m2) | 83.10 ± 8.64 | 99.85 ± 3.13 | 110.26 ± 3.07 | 123.40 ± 5.70 |  < 0.001 |
Gender |  |  |  |  |  < 0.001 |
 Male | 4455 (72.64%) | 4159 (67.77%) | 4044 (65.93%) | 3607 (58.77%) |  |
 Female | 1678 (27.36%) | 1978 (32.23%) | 2090 (34.07%) | 2530 (41.23%) |  |
Smoking status |  |  |  |  |  < 0.001 |
 Never smoker | 4237 (69.09%) | 4293 (69.95%) | 4466 (72.81%) | 4852 (79.06%) |  |
 Ever smoker | 250 (4.08%) | 275 (4.48%) | 274 (4.47%) | 275 (4.48%) |  |
 Current smoker | 1646 (26.84%) | 1569 (25.57%) | 1394 (22.73%) | 1010 (16.46%) |  |
Drinking status |  |  |  |  |  < 0.001 |
 Never drinker | 4948 (80.68%) | 4955 (80.74%) | 4909 (80.03%) | 5140 (83.75%) |  |
 Ever drinker | 914 (14.90%) | 951 (15.50%) | 1001 (16.32%) | 883 (14.39%) |  |
 Current drinker | 271 (4.42%) | 231 (3.76%) | 224 (3.65%) | 114 (1.86%) |  |
Family history of diabetes |  |  |  |  |  < 0.001 |
 No | 6035 (98.40%) | 6011 (97.95%) | 5963 (97.21%) | 5914 (96.37%) |  |
 Yes | 98 (1.60%) | 126 (2.05%) | 171 (2.79%) | 223 (3.63%) |  |