Skip to main content

Table 3 Factors influencing reversion to normoglycemia among participants with IFG analyzed by univariate Cox proportional hazards regression

From: Association between estimated glomerular filtration rate and reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study

Variable

Statistics

HR (95%CI)

P value

Age (years)

49.248 ± 13.770

0.976 (0.974, 0.977)

 < 0.00001

Gender

   

 Male

16,265 (66.277%)

Ref

 

 Female

8276 (33.723%)

1.267 (1.220, 1.317)

 < 0.00001

BMI (kg/m2)

24.811 ± 3.367

0.934 (0.929, 0.940)

 < 0.00001

SBP (mmHg)

127.116 ± 17.562

0.989 (0.988, 0.990)

 < 0.00001

DBP (mmHg)

78.360 ± 11.134

0.985 (0.983, 0.986)

 < 0.00001

FPG (mmol/L)

5.946 ± 0.318

0.222 (0.206, 0.240)

 < 0.00001

TC (mmol/L)

4.982 ± 0.956

0.877 (0.860, 0.894)

 < 0.00001

TG (mmol/L)

1.792 ± 1.444

0.891 (0.877, 0.905)

 < 0.00001

HDL-c (mmol/L)

1.327 ± 0.304

1.669 (1.575, 1.769)

 < 0.00001

LDL-c (mmol/L)

2.889 ± 0.720

0.911 (0.887, 0.935)

 < 0.00001

ALT (U/L)

28.531 ± 23.621

0.993 (0.992, 0.994)

 < 0.00001

AST (U/L)

26.365 ± 12.016

0.986 (0.985, 0.988)

 < 0.00001

BUN (mmol/L)

4.980 ± 1.219

0.954 (0.939, 0.969)

 < 0.00001

Scr (umol/L)

72.487 ± 15.046

0.997 (0.996, 0.998)

 < 0.00001

eGFR (mL/min·1.73 m2)

104.157 ± 15.778

1.013 (1.011, 1.014)

 < 0.00001

Smoking status

   

 Never smoker

17,848 (72.727%)

Ref.

 

 Ever smoker

1074 (4.376%)

0.882 (0.803, 0.968)

0.00838

 Current smoker

5619 (22.896%)

0.783 (0.747, 0.820)

 < 0.00001

Drinking status

   

 Never drinker

19,952 (81.301%)

Ref.

 

 Ever drinker

3749 (15.276%)

0.945 (0.897, 0.995)

0.03048

 Current drinker

840 (3.423%)

0.779 (0.696, 0.871)

0.00001

Family history of diabetes

   

 No

23,923 (97.482%)

Ref.

 

 Yes

618 (2.518%)

0.760 (0.671, 0.861)

0.00002

  1. BMI body mass index, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, TG triglyceride, DBP diastolic blood pressure, AST aspartate aminotransferase, TC total cholesterol, ALT alanine aminotransferase, SBP systolic blood pressure, LDL-c low-density lipid cholesterol, Scr serum creatinine, HDL-c high-density lipoprotein cholesterol, BUN blood urea nitrogen HR Hazard ratios, Ref reference, CI confidence interval