Association between estimated glomerular filtration rate and reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study

Table 6 Relationship between eGFR and the probability of reverting from IFG to normoglycemia in different sensitivity analyses

Exposure	Model a (HR, 95% CI, P)	Model b (HR, 95% CI, P)	Model c (HR, 95% CI, P)	Model d (HR, 95% CI, P)
eGFR	1.011 (1.010, 1.013) < 0.0001	1.008 (1.006, 1.009) < 0.0001	1.009 (1.007, 1.010) < 0.0001	1.008 (1.006, 1.009) < 0.0001
eGFR (Quartile)
Q1	Ref.	Ref.	Ref.	Ref.
Q2	1.029 (0.941, 1.126) 0.5265	1.018 (0.951, 1.090) 0.6020	1.031 (0.967, 1.099) 0.3452	1.010 (0.954, 1.070) 0.7234
Q3	1.094 (1.000, 1.196) 0.0499	1.102 (1.030, 1.178) 0.0045	1.112 (1.043, 1.185) 0.0011	1.073 (1.014, 1.136) 0.0148
Q4	1.338 (1.223, 1.463) < 0.0001	1.301 (1.217, 1.390) < 0.0001	1.372 (1.288, 1.462) < 0.0001	1.317 (1.244, 1.394) < 0.0001
P for trend	< 0.0001	< 0.0001	< 0.0001	< 0.0001

Model a was a sensitivity analysis conducted on 19,995 participants without eGFR < 90 mL/min·1.73 m². We adjusted for SBP, family history of diabetes, BMI, gender, DBP, FPG, TG, ALT, HDL-c, BUN, AST, LDL-c, smoking and drinking status
Model b was a sensitivity analysis performed on 17,848 participants who had never smoked. We adjusted for SBP, family history of diabetes, BMI, gender, DBP, FPG, TG, ALT, HDL-c, BUN, AST, LDL-c, and drinking status
Model c was a sensitivity analysis conducted on 19,952 participants who had never consumed alcohol. We adjusted for SBP, family history of diabetes, BMI, gender, DBP, FPG, TG, ALT, HDL-c, BUN, AST, LDL-c, and smoking status
Model d was a sensitivity analysis carried out on 173,301 participants without adjusting for smoking and drinking status. We adjusted for SBP, family history of diabetes, BMI, gender, DBP, FPG, TG, ALT, HDL-c, BUN, AST, LDL-c
HR hazard ratios, Ref. reference, CI confidence, eGFR estimated glomerular filtration rate (mL/min·1.73 m²)

ISSN: 2047-783X