Association between estimated glomerular filtration rate and reversion to normoglycemia in people with impaired fasting glucose: a 5-year retrospective cohort study

Table 7 Result of the two-piecewise Cox regression model

reversion to normoglycemia	Model* (HR, 95%CI, P)	Model^# (HR, 95%CI, P)
Fitting model by standard Cox regression	1.008 (1.006, 1.009) < 0.0001	1.011 (1.010, 1.013) < 0.0001
Fitting model by two-piecewise Cox regression
Inflection point of eGFR	111.962	112.029
≤ Inflection point	1.003 (1.001, 1.005) 0.0064	1.005 (1.001, 1.008) 0.0161
> Inflection point	1.019 (1.015, 1.022) < 0.0001	1.018 (1.015, 1.022) < 0.0001
P for log-likelihood ratio test	< 0.001	< 0.001

Model *: analysis among all participants; Model I#: sensitivity analysis in participants without eGFR < 90 mL/min·1.73 m² (N = 19,995)
We adjusted SBP, family history of diabetes, BMI, gender, DBP, FPG, TG, ALT, HDL-c, BUN, AST, LDL-c, smoking and drinking status
HR, Hazard ratios; Ref reference; CI confidence, eGFR, estimated glomerular filtration rate (mL/min·1.73 m²)

ISSN: 2047-783X