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Fig. 3 | European Journal of Medical Research

Fig. 3

From: Downregulation of salusins alleviates hypertrophic cardiomyopathy via attenuating oxidative stress and autophagy

Fig. 3

Attenuation of cardiac fibrosis via TOR2A downregulation. a–b The increase of cardiac fibrosis in the rats infused with Ang II was suppressed by TOR2A downregulation. The increased levels of collagen I, collagen III and TGF-β in the heart of Ang II-infused rats (c) and Ang II-treated NRCFs (d) were inhibited by TOR2A downregulation. Data are expressed as the mean ± SEM. N = 6 in each group. Scale bar: 100 μm. Ang angiotensin, TOR2A torsin family 2 member A, TGF-β transforming growth factor-beta, NRCFs neonatal rat cardiac fibroblasts

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