Table 1 Patient characteristics
Asthma group (N = 192) | COPD group (N = 135) | ACO group (N = 70) | P-value | |
|---|---|---|---|---|
Age, year | 46.0 (33.0, 55.5) | 61.0 (56.0, 66.0) | 56.0 (50.5, 62.3) | < 0.001 |
Sex (female/male), N | 121/71 | 19/116 | 7/63 | < 0.001 |
BMI, kg/m2 | 23.5 ± 3.5 | 22.9 ± 3.8 | 23.7 ± 2.9 | 0.178 |
Smoking history | ||||
Current or ex-smoker/nonsmoker, N | 38/154 | 111/24 | 53/17 | < 0.001 |
Smoking pack-years | 0.0 (0.0, 0.0) | 30.0 (10.0, 40.0) | 20.0 (0.0, 31.3) | < 0.001 |
Pulmonary function grading (normal/mild/moderate/moderate to severe/severe/extremely severe), N | 32/70/37/26/21/7 | 0/19/30/22/41/23 | 0/23/17/9/12/9 | < 0.001 |
Post-bronchodilation spirometry | ||||
FEV1, L | 1.91 (1.43, 2.44) | 1.43 (1.02, 1.71) | 1.75 (1.24, 2.08) | < 0.001 |
Predicted FEV1, % | 69.7 ± 18.4 | 53.5 ± 18.1 | 61.7 ± 21.3 | < 0.001 |
FVC, L | 3.08 (2.53, 3.74) | 2.90 (2.55, 3.34) | 3.23 (2.55, 3.62) | 0.004 |
Predicted FVC, % | 96.5 ± 18.4 | 86.8 ± 17.9 | 90.4 ± 21.4 | < 0.001 |
FEV1/FVC, % | 60.7 ± 11.3 | 48.1 ± 11.6 | 53.9 ± 11.4 | < 0.001 |
△FEV1, mL | 340.0 (280.0, 480.0) | 260.0 (230.0, 290.0) | 425.0 (327.5, 530.0) | < 0.001 |
△FVC, mL | 210.0 (92.5, 367.5) | 300.0 (170.0, 470.0) | 425.0 (117.5, 567.5) | < 0.001 |
Standard I, N(%) | 66 (34.4) | 4 (3.0) | 40 (50.7) | < 0.001 |
Standard II, N(%) | 74 (38.5) | 4 (3.0) | 42 (60) | < 0.001 |
Standard III, N(%) | 135 (70.3) | 103 (76.3) | 61 (87.1) | 0.019 |
FeNO, ppb | 44.0 (17.0, 78.3) | 21.0 (14.0, 51.0) | 32.5 (20.8, 54.3) | 0.003 |
Blood parameters | ||||
Total eosinophils, /μL | 340 (175, 493) | 230 (130, 410) | 255 (133, 465) | 0.107 |
%Eosinophils | 5.1 ± 3.5 | 3.9 ± 2.9 | 4.5 ± 3.4 | 0.251 |