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Table 3 Predictive values for predicting ACO diagnosis from COPD in patients with a positive BDT result

From: The value of bronchodilator response in FEV1 and FeNO for differentiating between chronic respiratory diseases: an observational study

ΔFEV1 (mL)

Sensibility (%)

Specificity (%)

PPV (%)

NPV (%)

Youden index

345

72.9

91.1

81.0

86.6

0.640

355

70.0

91.9

81.7

85.5

0.619

365

68.6

94.1

85.7

85.2

0.627

375

67.1

94.8

87.0

84.8

0.619

385

65.7

95.6

88.5

84.3

0.613

  1. COPD, chronic obstructive pulmonary disease; ACO, asthma–chronic obstructive pulmonary disease overlap; BDT, bronchodilation test; FEV1, forced expiratory volume in 1 s; PPV, positive predictive values; NPV, negative predictive values