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Table 4 Predictive values for predicting asthma diagnosis in patients with a positive BDT result

From: The value of bronchodilator response in FEV1 and FeNO for differentiating between chronic respiratory diseases: an observational study

 

AUC

Cutoff value

Sensibility (%)

Specificity (%)

PPV (%)

NPV (%)

Youden index

P-value

FeNO (ppb)

0.613 (95% CI 0.55–0.68)

28.5

61.9

63.2

70.9

53.4

0.251

0.001

ΔFEV1 (mL)

0.765 (95% CI 0.71–0.82)

315

59.7

86.4

85.0

59.3

0.461

 < 0.001

FeNO + ΔFEV1

0.774 (95% CI 0.72–0.83)

–

61.3

86.4

93.4

52.2

0.477

 < 0.001

  1. BDT, bronchodilation test; FeNO, fractional exhaled nitric oxide; FEV1, forced expiratory volume in 1 s; AUC, area under the curve; PPV, positive predictive values; NPV, negative predictive values
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European Journal of Medical Research

ISSN: 2047-783X

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