Fig. 2From: Unraveling the causality between chronic obstructive pulmonary disease and its common comorbidities using bidirectional Mendelian randomizationPreliminary UVMR assessments of the associations between genetic susceptibility to COPD and its prevalent comorbidities. Purple boxes denote positive correlations, while light blue boxes signify negative associations. The asterisk “*” represents P-values of MR estimates between the Bonferroni-adjusted threshold (P < 0.0021) and 0.05. The double asterisk “**” designates P < 0.0021Back to article page