Table 1 Cox regression analysis of the association between BAG3 expression and clinical characteristics of TCGA cohort
Characteristics | Total (N) | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|---|
Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | ||
Age | 539 | Â | Â | Â | Â |
  ≤ 60 | 269 | Reference |  |  |  |
  > 60 | 270 | 1.765 (1.298–2.398) |  < 0.001 | 1.632 (1.192–2.233) | 0.002 |
Gender | 539 | Â | Â | Â | Â |
 Female | 186 | Reference |  |  |  |
 Male | 353 | 0.930 (0.682–1.268) | 0.648 |  |  |
T stage | 539 | Â | Â | Â | Â |
 T1&T2 | 349 | Reference |  |  |  |
 T3&T4 | 190 | 3.228 (2.382–4.374) |  < 0.001 | 1.668 (1.163–2.392) | 0.005 |
M stage | 506 | Â | Â | Â | Â |
 M0 | 428 | Reference |  |  |  |
 M1 | 78 | 4.389 (3.212–5.999) |  < 0.001 | 2.829 (1.976–4.051) |  < 0.001 |
Histologic grade | 531 | Â | Â | Â | Â |
 G1&G2 | 249 | Reference |  |  |  |
 G3&G4 | 282 | 2.702 (1.918–3.807) |  < 0.001 | 1.709 (1.186–2.462) | 0.004 |
BAG3 | 539 | Â | Â | Â | Â |
 Low | 269 | Reference |  |  |  |
 High | 270 | 0.584 (0.430–0.794) |  < 0.001 | 0.696 (0.509–0.950) | 0.023 |