Fig. 5
After knocking down the expression of LBX2-AS1 in renal carcinoma cells, overexpression of FOXO3 can partially restore the proliferation, invasion and migration of renal clear cell carcinoma. A RT-qPCR verified the efficiency of overexpression of FOXO3 by lentivirus. (****P < 0.0001). B, C The results of CCK8 and cell cloning tests showed that overexpression of FOXO3 cocoa partially restored the proliferation ability of renal clear cell carcinoma after low expression of LBX2-AS1 (*P < 0.05, **P < 0.01). D, E Scratch test and transwell test showed that overexpression of FOXO3 cocoa partially restored the migration and invasion ability of renal clear cell carcinoma after low expression of LBX2-AS1 (*P < 0.05, **P < 0.01)