Causal relationships between delirium and Parkinson’s disease: a bidirectional two-sample Mendelian randomization study

Table 1 The result of the MR study and reverse MR study

Exposure	Outcome	Method	SNP (n)	β	se	P-value	OR (95CI%)
Delirium	PD	MR Egger	8	0.003	0.028	0.916	1.003 (0.950–1.060)
		Weighted median	8	− 0.006	0.028	0.816	0.993 (0.939–1.050)
		Inverse variance weighted	8	− 0.004	0.022	0.845	0.996 (0.949–1.043)
		Weighted mode	8	− 0.005	0.028	0.864	0.995 (0.938–1.051)
PD	Delirium	MR Egger	22	0.215	0.132	0.120	1.241 (0.795–1.684)
		Weighted median	22	0.126	0.088	0.153	1.135 (0.891–1.391)
		Inverse variance weighted	22	0.076	0.062	0.225	1.078 (0.960–1.204)
		Weighted mode	22	0.204	0.141	0.162	1.226 (0.915–1.597)

OR, odds ratio, CI confidence interval, MR Mendelian randomization, SNPs single nucleotide polymorphisms, NA not available
^*The statistically significant difference with a P-value less than 0.05 (P < 0.05)

ISSN: 2047-783X