Changes of Mycobacterium tuberculosis specific antigen-stimulated CD27−CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment

Table 1 Characteristics of the participants

	PTB (n = 26)	LTBI (n = 38)	HC (n = 43)	P*
Male (n, %)	16 (61.5%)	15 (39.5%)	16 (37.2%)	P = 0.1126
Age (year)	35.2 ± 13.5	44.6 ± 13.9	36.5 ± 12.8	P = 0.007
TB culture**
N/A (n, %)	0	0	0
Negative (n, %)	0	38 (100%)	43 (100%)
Positive (n, %)	26(100%)	0	0
IGRA**
N/A (n, %)	1 (3.8%)	0	0
Negative (n, %)	1 (3.8%)	0	43 (100%)
Positive (n, %)	24 (92.3%)	38 (100%)	0

PTB pulmonary tuberculosis, LTBI latent tuberculosis infection, HC healthy control, N/A not available
^*Statistical analyses for age data analyzed using the ordinary one-way ANOVA (3 groups): P = 0.007; unpaired t test (2 groups): PTB and LTBI P = 0.093; PTB and HC P = 0.7
Statistical analyses for sex data analyzed using the Chi-square test
^**Before initiation of anti-tuberculous therapy

ISSN: 2047-783X