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Table 2 Performance of different phenotypic markers

From: Changes of Mycobacterium tuberculosis specific antigen-stimulated CD27CD38+IFN-γ+CD4+ T cells before and after anti-tuberculosis treatment

 

Cutoff (%)

Se (%)

Sp (%)

FPR

FNR

PPV (%)

NPV (%)

 + LR

−LR

Youden

CD27CD38+

55.41

61.54

84.62

15.38

38.46

80

68.75

4

0.455

0.4616

CD27

46.9

76.92

73.08

26.92

23.08

74.07

76

2.857

0.316

0.50

CD38+

30.82

100

26.92

73.08

0

57.78

100

1.368

0.000

0.2692

  1. Se sensitivity, Sp specificity, FPR false positive rate, FNR false-negative rate, PPV positive predictive value, NPV negative predictive value, +LR positive likelihood ratio, LR negative likelihood ratio