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Table 2 Stability and reliability during long-term storage

From: Reliability, stability during long-term storage, and intra-individual variation of circulating levels of osteopontin, osteoprotegerin, vascular endothelial growth factor-A, and interleukin-17A

 

% change per year [95% CI]

Intra-assay CV [95% CI]

Inter-assay CV [95% CI]

OPN

− 0.3% [− 4.2, 3.8]

0.041 [0.032, 0.053]

0.059 [0.032, 0.11]

OPGa

− 33% [− 54, − 3.7]

0.12 [0.095, 0.16]

0.076 [0.022, 0.26]

VEGF-Ab

− 6.3% [− 14, 1.8]

0.069 [0.055, 0.088]

0.20 [0.11, 0.36]

IL-17Ab

− 70% [− 83, − 48]

0.85 [0.37, 2.91]

0.43 [0.36, 0.52]

  1. Based on a mixed model, estimated by REML method, with a fixed effect of storage duration:
  2. aAdjusted for the fixed effects of measurement environment (combination of kit and platform software) and b adjusted for the fixed effect of platform software