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Table 3 Primary and secondary outcome analyses with different models for cohort 1 and cohort 2

From: The optimal blood glucose is significantly associated with lower mortality in critically ill patients with cardiogenic shock: an analysis revealed with time series blood glucose records

 

Cohort 1 1

p-value

Cohort 2 2

p-value

28-day mortality

    

Log-rank test [HR (95% CI)]3

1.67 (1.19, 2.33)

 < 0.01

1.72 (1.46, 2.03)

 < 0.001

Multivariate Cox model adjusted with all covariates [HR (95% CI)]3

1.58 (1.12, 2.22)

 < 0.01

1.15 (1.08, 1.22)

 < 0.001

Multivariate Cox model adjusted with unbalanced covariates [HR (95% CI)]3

1.61 (1.16, 2.25)

 < 0.01

1.15 (1.08, 1.22)

 < 0.001

Cox model adjusted with all covariates using IPTW [HR (95% CI)]3

1.89 (1.16, 3.07)

 < 0.05

1.38 (1.08, 1.76)

 < 0.01

Survey-weighted Cox model adjusted with all covariates using IPTW [HR (95% CI)]3

1.91 (1.17, 3.12)

 < 0.01

1.10 (1.02, 1.18)

 < 0.05

ICU mortality

    

Log-rank test [HR (95% CI)]3

2.30 (1.40, 3.79)

 < 0.001

1.77 (1.45, 2.17)

 < 0.001

Multivariate Cox model adjusted with all covariates [HR (95% CI)]3

2.29 (1.41, 3.73)

 < 0.001

1.87 (1.45, 2.41)

 < 0.001

Multivariate Cox model adjusted with unbalanced covariates [HR (95% CI)]3

2.30 (1.46, 3.62)

 < 0.001

1.82 (1.42, 2.34)

 < 0.001

Cox model adjusted with all covariates using IPTW [HR (95% CI)]3

1.38 (1.12, 1.71)

 < 0.01

1.38 (1.01, 1.87)

 < 0.05

Survey-weighted Cox model adjusted with all covariates using IPTW [HR (95% CI)]3

2.81 (1.42, 5.57)

 < 0.01

1.38 (1.01, 1.88)

 < 0.05

In-hospital mortality

    

Log-rank test [HR (95% CI)]3

1.73 (1.19, 2.51)

 < 0.01

1.64 (1.38, 1.95)

 < 0.001

Multivariate Cox model adjusted with all covariates [HR (95% CI)]3

1.89 (1.29, 2.75)

 < 0.001

1.66 (1.34, 2.06)

 < 0.001

Multivariate Cox model adjusted with unbalanced covariates [HR (95% CI)]3

1.95 (1.35, 2.80)

 < 0.001

1.15 (1.08, 1.23)

 < 0.001

Cox model adjusted with all covariates using IPTW [HR (95% CI)]3

2.07 (1.23, 3.48)

 < 0.01

1.32 (1.02, 1.71)

 < 0.05

Survey-weighted Cox model adjusted with all covariates using IPTW [HR (95% CI)]3

2.09 (1.24, 3.52)

 < 0.01

1.08 (1.00, 1.17)

 < 0.05

  1. Statistical analyses of different models with p-value < 0.05 were displayed in bold
  2. 1Cohort 1: optimal TWA-BG (104 < TWA-BG ≤ 138 mg/dL) versus low TWA-BG (TWA-BG ≤ 104 mg/dL)
  3. 2Cohort 2: optimal TWA-BG (104 < TWA-BG ≤ 138 mg/dL) versus high TWA-BG (TWA-BG > 138 mg/dL)
  4. 3HR = hazard ratio, CI = confidence interval
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European Journal of Medical Research

ISSN: 2047-783X

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