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Table 2 Association of triglyceride glucose index with clinical outcomes by tertiles

From: Association of triglyceride glucose index with cardiovascular events: insights from the Isfahan Cohort Study (ICS)

 

Model 1

Model 2

Model 3

Model 4

Model 5

Cardiovascular disease

 Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Tertile 2

1.34 (1.11–1.61)

1.25 (1.04–1.51)

1.25 (1.04–1.51)

1.27 (1.05–1.53)

1.14 (0.93–1.38)

 Tertile 3

1.91 (1.60–2.27)

1.73 (1.46–2.07)

1.71 (1.44–2.04)

1.70 (1.42–2.02)

1.48 (1.22–1.79)

 P for trend†

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 < 0.001

Myocardial infarction

 Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Tertile 2

1.62 (1.03–2.54)

1.55 (0.98–2.43)

1.53 (0.97–2.40)

1.58 (1.01–2.48)

1.45 (0.91–2.32)

 Tertile 3

2.64 (1.75–3.99)

2.46 (1.63–3.72)

2.45 (1.62–3.71)

2.52 (1.66–3.82)

2.24 (1.42–3.52)

 P for trend†

 < 0.001

 < 0.001

 < 0.001

 < 0.001

 < 0.001

Stroke

 Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Tertile 2

1.14 (0.75–1.72)

1.04 (0.69–1.58)

1.04 (0.69–1.57)

1.06 (0.70–1.61)

0.99 (0.64–1.53)

 Tertile 3

1.83 (1.26–2.64)

1.63 (1.12–2.36)

1.55 (1.07–2.25)

1.55 (1.07–2.26)

1.45 (0.96–2.19)

 P for trend†

0.001

0.005

0.011

0.012

0.042

Unstable angina

 Tertile 1

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

1 (Ref.)

 Tertile 2

1.35 (1.03–1.77)

1.27 (0.69–1.67)

1.27 (0.97–1.67)

1.25 (0.95–1.64)

1.07 (0.81–1.43)

 Tertile 3

1.79 (1.39–2.31)

1.62 (1.26–2.09)

1.61 (1.25–2.08)

1.55 (1.19–2.00)

1.28 (0.96–1.69)

 P for trend†

 < 0.001

 < 0.001

 < 0.001

0.001

0.062

  1. Model 1: crude
  2. Model 2: adjusted for age (years) and sex (man/woman)
  3. Model 3: additionally, adjusted for education level (0–5 years/6–12 years/ > 12 years), marital status (married/not married), and residency location (urban/rural)
  4. Model 4: additionally adjusted for global dietary index (GDI), smoking status (never smoked/ever smoked), and total daily physical activity (MET-min/day)
  5. Model 5: additionally, adjusted for BMI (kg/m2), hypertension (yes/no), and high total cholesterol (yes/no)
  6. †Derived from a Mantel‒Haenszel extension for Chi-square test