Table 7 The symbols and full names of the predicted proteins in the PPI networks
From: Cortical lipid metabolic pathway alteration of early Alzheimer’s disease and candidate drugs screen
No. | Accession no. | Protein symbol | Full name | Score |
|---|---|---|---|---|
Up-regulated network | ||||
1 | P80404 | ABAT | 4-Aminobutyrate aminotransferase, mitochondrial | 0.997 |
2 | P30084 | ECHS1 | Enoyl-CoA hydratase, mitochondrial | 0.992 |
3 | Q9BQ95 | ECSIT | Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial | 0.994 |
4 | O14842 | FFAR1 | Free fatty acid receptor 1 | 0.993 |
5 | P03923 | MT-ND6 | NADH-ubiquinone oxidoreductase chain 6 | 0.992 |
6 | Q9Y375 | NDUFAF1 | Complex I intermediate-associated protein 30, mitochondrial | 0.996 |
7 | Q9BU61 | NDUFAF3 | NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 | 0.995 |
8 | O75306 | NDUFS2 | NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial | 0.995 |
9 | Q8IUX1 | TMEM126B | Complex I assembly factor TMEM126B, mitochondrial | 0.997 |
10 | Q7L0Y3 | TRMT10C | tRNA methyltransferase 10 homolog C | 0.994 |
Down-regulated network | ||||
1 | P11310 | ACADM | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 0.996 |
2 | Q0VD83 | APOB | Apolipoprotein B-100 | 0.996 |
3 | P02649 | APOE | Apolipoprotein E | 0.996 |
4 | Q92851 | CASP10 | Caspase-10 | 0.999 |
5 | O15519 | CASP8 | Caspase-8 | 0.999 |
6 | O15519 | CFLAR | CASP8 and FADD-like apoptosis regulator | 0.999 |
7 | P48023 | FADD | FAS-associated death domain protein | 0.999 |
8 | P48023 | FASLG | Tumor necrosis factor ligand superfamily member 6 | 0.998 |
9 | Q92851 | PCSK9 | Proprotein convertase subtilisin/kexin type 9 | 0.999 |
10 | Q12772 | SREBF2 | Sterol regulatory element-binding protein 2 | 0.994 |