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Table 1 Baseline characteristics of patients with PsA

From: Serum proteome analysis identifies a potential biomarker for axial psoriatic arthritis

 

Discovery cohort

Verification cohort

axPsA (n = 20)

pPsA(n = 20)

P

axPsA (n = 37)

pPsA(n = 51)

P

Gender (male), n (%)

14 (70.0)

9 (45.0)

0.110

27 (73.0)

20 (39.2)

0.002

Age, mean (SD)

41.8 (11.9)

40.1 (11.4)

0.647

43.8 (11.1)

42.2 (10.2)

0.696

Comorbidity

  Hypertension, n (%)

4 (20.0)

4 (20.0)

1.000

9 (24.3)

9 (17.6)

0.443

  Diabetes, n (%)

1 (5.0)

0 (0.0)

1.000

3 (8.1)

1 (2.0)

0.305

  Hyperlipidemia, n (%)

6 (30.0)

5 (25.0)

0.723

8 (21.6)

10 (19.6)

0.817

Ever smoker, n (%)

11 (55.0)

6 (30.0)

0.110

20 (54.1)

10 (19.6)

0.001

BMI, mean (SD)

24.7 (5.0)

25.8 (4.3)

0.452

25.1 (21.8, 27.8)a

24.3 (22.0, 27.1)a

0.826

SJC, median (IQR)

2.0 (0.3, 3.8)

3.5 (0.3, 5.5)

0.317

1.0 (0.0, 4.0)

3.0 (0.0, 6.0)

0.131

TJC, median (IQR)

2.0 (0.3, 6.0)

6.4 (1.8, 10.5)

0.141

1.5 (0.0, 6.0)

4.5 (2.0, 8.8)

0.012

Extra-articular manifestations (current)

 PASI, median (IQR)

2.7 (0.4, 21.4)

1.4 (0.0, 3.4)

0.031

3.0 (0.3, 16.3)

1.3 (0.1, 3.3)

0.081

 Enthesitis, n (%)

6 (16.2)

14 (27.5)

0.214

6 (16.2)

14 (27.5)

0.304

 Dactylitis, n (%)

2 (10.0)

3 (15.0)

1.000

5 (13.5)

7 (13.7)

0.977

Extra-articular manifestations (ever)

  Dactylitis, n (%)

4 (20.0)

4 (20.0)

1.000

10 (27.0)

12 (23.5)

0.708

  Enthesitis, n (%)

11 (55.0)

12 (60.0)

1.000

21 (56.8)

31 (60.8)

0.704

  IBD, n (%)

0 (0.0)

0 (0.0)

/

1 (2.7)

2 (3.9)

1.000

  Uveitis, n (%)

1 (5.0)

1 (5.0)

1.000

4 (10.8)

1 (2.0)

0.157

CRP, median (IQR)

9.8 (4.8, 33.2)

4.5 (1.1, 28.9)

0.176

8.4 (3.8, 26.8)

2.7 (0.9, 13.0)

0.005

ESR, median (IQR)

27.5 (12.0, 63.3)

12 (3.5, 27.7)

0.085

14 (10.0, 38.0)

11.0 (4.3, 22.5)

0.043

HLA-B27 (+), n (%)

8 (40.0)

2 (10.0)

0.028

12 (38.7)

4 (8.7)

0.001

DAPSA, median (IQR)

19.6 (10.4, 29.7)

20.5 (10.2, 27.9)

0.968

14.9 (8.4, 27.3)

18.3 (10.3, 26.2)

0.455

DAS28-CRP, mean (SD)

3.9 (1.9)

3.5 (1.4)

0.610

3.3 (1.4)

3.3 (1.2)

0.869

DAS28-ESR, mean (SD)

3.6 (1.4)

3.4 (1.2)

0.472

3.4 (1.7)

3.4 (1.3)

0.887

  1. axPsA axial psoriatic arthritis, pPsA peripheral psoriatic arthritis, BMI body mass index, SJC swollen joint count, TJC tender joint count, PASI psoriasis area and severity index, IBD inflammatory bowel disease, CRP C-reactive protein, ESR erythrocyte sedimentation rate, DAPSA disease activity index for psoriatic arthritis, DAS28 disease activity score 28
  2. aData were described with median (IQR)
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European Journal of Medical Research

ISSN: 2047-783X

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