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Table 4 Odds of cognitive impairment by number of vascular beds involved among individuals with and without chronic kidney disease (Firth’s logistic regression)

From: Polyvascular atherosclerosis and renal dysfunction increase the odds of cognitive impairment in vascular disease: findings of the LipidCardio study

 

Adjusted* odds ratio (95% confidence interval)

p-value

CKD (n = 214)

 0 vascular beds

1.0 (reference)

 1 vascular bed#

4.60 (1.35–23.98)

0.012

 ≥ 2 vascular beds+

4.24 (1.04–24.37)

0.043

No CKD (n = 520)

 0 vascular beds

1.0 (reference)

 1 vascular bed#

0.98 (0.48–2.10)

0.095

 ≥ 2 vascular beds+

2.71 (1.10–6.92)

0.031

  1. CKD, chronic kidney disease, # monovascular atherosclerotic disease, +polyvascular atherosclerotic disease; *adjusted for age group, sex, APO e4 carrier status, body-mass index, current smoking, diabetes mellitus, hypertension