Fig. 7
From: CD133 significance in glioblastoma development: in silico and in vitro study
The colony formation and mRNA expression of SOX2. A The microscopic image of the clonogenicity of the control group. B The microscopic image of the clonogenicity of the temozolomide group. C The microscopic image of the clonogenicity of the CD133-siRNA group. D The microscopic image of the clonogenicity of the combined therapy. CD133 silencing decreases the clonogenicity of U87MG cells. E The mRNA expression of SOX2 in different studied groups. CD133 silencing downregulates the expression of SOX2 in U87MG cells. *P-value ≤ 0.05, and ****P-value ≤ 0.0001