Table 3 Spearman correlations between enzyme serum levels

MMP3 day 0

MMP10 day 0

MMP13 day 0

MMP3 day 0

1

0.663**

0.895**

MMP10 day 0

0.663**

1

0.564**

MMP13 day 0

0.895**

0.564**

1

MMP3 day 1

MMP10 day 1

MMP13 day 1

MMP3 day 1

1

0.747**

0.967**

MMP10 day 1

0.747**

1

0.741**

MMP13 day 1

0.967**

0.741**

1

MMP3 day 3

MMP10 day 3

MMP13 day 3

MMP3 day 3

1

0.536**

0.937**

MMP10 day 3

0.536**

1

0.512**

MMP13 day 3

0.937**

0.512**

1

MMP3 day 5

MMP10 day 5

MMP13 day 5

MMP3 day 5

1

0.717**

0.911**

MMP10 day 5

0.717**

1

0.687**

MMP13 day 5

0.911**

0.687**

1

MMP3 day 7

MMP10 day 7

MMP13 day 7

MMP3 day 7

1

0.474*

0.769**

MMP10 day 7

0.474*

1

0.599**

MMP13 day 7

0.769**

0.599**

1

MMP3 day 10

MMP10 day 10

MMP13 day 10

MMP3 day 10

1

0.547*

0.614**

MMP10 day 10

0.547*

1

0.366

MMP13 day 10

0.614**

0.366

1