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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Photodynamic therapy upregulates expression of HIF-1α and PD-L1 in related pathways and its clinical relevance in non-small-cell lung cancer

Fig. 2

Enrichment analysis and PPI network of candidate genes in NSCLC-PDT database. A The Venn diagram of DEGs from datasets from GEO and GeneCards database. B Bubble chart of GO enrichment analysis of candidate genes. C Bubble chart of KEGG enrichment analysis of candidate genes. D PPI network of candidate genes using the STRING database. Red represents HIF-1 pathway-related genes, purple represents PD-L1 and PD-1 checkpoint pathway-related genes, and green represents PDT-induced HIF-1 signaling pathway-related genes. E Bar chart of the TOP25 genes based on degree value. F The correlation of significant modules in PPI network. The node size was varied by PPI degrees, and the color was different with MCODE scores

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European Journal of Medical Research

ISSN: 2047-783X

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