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Table 3 Results of meta-analysis, heterogeneity, publication bias, power analysis and prediction interval of biomarkers

From: Evaluating biomarkers for contrast-induced nephropathy following coronary interventions: an umbrella review on meta-analyses

Variable

Odds ratio

95% CI, P value

Heterogeneity

P vale of publication bias based on eagers regression test

Power analysis

Prediction interval

Hypoalbuminemia

3.09

1.43–6.63, P < 0.01

90%, P < 0.01

P = 0.17

1-b = 1

0.17–53.56

Hyperuricemia

1.32

1.15–1.50, P < 0.01

88%, P < 0.01

P < 0.01

1-b = 0.99

0.86–2.00

BUN

1.06

0.97–1.15, P = 0.18

88%, P < 0.01

P = 0.52

1-b = 0.05

0.38–2.91

CRP

1.06

1.00–1.12, P = 0.04

98%, P < 0.01

P = 0.36

1-b = 0.15

0.86–1.31

HS-CRP

1.03

1.01–1.05, P = 0.01

50%, P = 0.04

P < 0.01

1-b = 0.12

0.98–1.08

NLR

1.10

1.01–1.20, P = 0.01

78%, P < 0.01

P = 0.26

1-b = 0.46

0.83–1.46

RDW

1.34

1.18–1.52, P < 0.01

0%, P = 0.73

P = 0.30

1-b = 0.70

1.18–1.52

Lower HCT

0.94

0.91–0.97, P < 0.01

69%, P < 0.01

P = 0.74

1-b = 0.33

0.86–1.03

PLR

1.11

0.99–1.24, P = 0.06

87%, P < 0.01

P = 0.09

1-b = 0.43

0.70–1.77

GGT

3.21

1.26–8.15, P = 0.01

91%, P < 0.01

P = 0.06

1-b = 1

0.03–266.17

BNP

8.93

5.99–13.30, P < 0.01

69%, P < 0.01

P = 0.06

1-b = 1

2.30–34.55

V/CR

2.61

1.93–3.53, P < 0.01

76%, P < 0.01

P < 0.01

1-b = 1

0.98–6.94

UKIM-1

13.51

7.95–22.97, P < 0.01

14%, P = 0.31

P = 0.01

1-b = 1

5.12–35.66

Preprocedural hyperglycemia over 140

1.70

1.34–2.15, P < 0.01

26%, P = 0.25

P = 0.45

1-b = 1

0.78–3.68

Preprocedural hyperglycemia over 200

2.06

1.87–2.28, P < 0.01

0%, P = 0.90

P = 0.30

1-b = 1

1.87–2.28

Cystatin-C

20.07

7.26–55.46, P < 0.01

88%, P < 0.01

P = 0.11

1-b = 1

0.51–776.18

NGAL

31.29

13.72–71. 34, P < 0.01

73%, P < 0.01

P < 0.01

1-b = 1

1.61–605.16

  1. Gamma-glutamyl transpeptidase, CRP: C-Reactive Protein, hsCRP: Highly Sensitive C-Reactive Protein, NLR: Neutrophil-to-lymphocyte ratio, RDW: red cell distribution width, PLR: Platelet-to-Lymphocyte Ratio, HCT: Hematocrit, BUN: Blood urea nitrogen, NGAL: Neutrophil gelatinase-associated lipocalin, uKIM-1: Urinary kidney injury molecule-1, BNP: Brain natriuretic peptide, V/Cr: Contrast volume to creatinine clearance