Skip to main content

Table 2 Summary of the mechanism of traditional Chinese medicine prescription

From: Research advances on molecular mechanism and natural product therapy of iron metabolism in heart failure

Traditional Chinese medicine prescription

Function

Reference

QDQXC

Upregulate the expression of system xc- and GPX4 through the Nrf2 signaling pathway

[231]

YQHXF

Downregulate AMPK and Beclin1 protein phosphorylation, upregulate SLC7A11 and GPX4 protein expression

[233]

SXBXW

Regulate the miR-144-3p/SLC7A11 signaling pathway

[238]

LHF

Upregulate of the SLC7A11/GPX4 pathway, activate the Keap-1/Nrf2/ARE antioxidant signaling pathway

[242, 243]

YXB

Activate the DJ-1/GPX4 signaling pathway

[245]