Table 3 Significance of serum PYCARD, IL-38, IL-6, ESR, and anti-CCP levels in predicting RA
From: Serum PYCARD may become a new diagnostic marker for rheumatoid arthritis patients
Factor | AUC | 95%CI | Optimal cut-off value | Sensitivity (%) | Specificity (%) | Youden’s index |
|---|---|---|---|---|---|---|
IL-38 | 0.85 | (0.7966, 0.9139) | 298.27 | 84.1 | 80.7 | 0.648 |
IL-6 | 0.82 | (0.7602, 0.894) | 2.25 | 81.8 | 77.3 | 0.591 |
PYCARD | 0.89 | (0.835, 0.9354) | 1291.6 | 85.2 | 81.8 | 0.67 |
ESR | 0.89 | (0.8294, 0.941) | 12.5 | 78.4 | 92 | 0.704 |
anti-CCP | 0.82 | (0.7471, 0.9003) | 12.5 | 79.5 | 98.9 | 0.784 |
IL-38/anti-CCP | 0.96 | 84.1 | 94.3 | 0.784 | ||
IL-6/anti-CCP | 0.96 | 98.9 | 89.8 | 0.887 | ||
PYCARD/anti-CCP | 0.97 | 96.6 | 87.5 | 0.841 |