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Fig. 3 | European Journal of Medical Research

Fig. 3

From: Competitive adsorption of microRNA-532-3p by circular RNA SOD2 activates Thioredoxin Interacting Protein/NLR family pyrin domain containing 3 pathway and promotes pyroptosis of non-alcoholic fatty hepatocytes

Fig. 3

circSOD2 competitively binds to miR-532-3p. A subcellular localization of circSOD2; B identification of 13 potential miRNAs interacting with circSOD2 via circRIP and bioinformatics analysis; C targeted interaction between circSOD2 and miR-532-3p validated by dual-luciferase reporter assay; D co-localization of circSOD2 and miR-532-3p assessed by FISH; E expression of miR-532-3p in liver tissues of NAFLD patients analyzed by RT-qPCR; F miR-532-3p expression in liver tissues of NAFLD rats assessed by RT-qPCR; G evaluation of miR-532-3p expression in PA-treated AML12 cells by RT-qPCR; H impact of circSOD2 knockdown on miR-532-3p levels determined by RT-qPCR; Data are presented as mean ± SD (n = 3).*P < 0.05

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European Journal of Medical Research

ISSN: 2047-783X

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