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Fig. 6 | European Journal of Medical Research

Fig. 6

From: Competitive adsorption of microRNA-532-3p by circular RNA SOD2 activates Thioredoxin Interacting Protein/NLR family pyrin domain containing 3 pathway and promotes pyroptosis of non-alcoholic fatty hepatocytes

Fig. 6

TXNIP is a downstream target gene of miR-532-3p. A Ten mRNAs with the highest AGO CLIP-seq sequencing data with miR-532-3p predicted by bioinformatics resource [https://starbase.sysu.edu.cn/]; B Targeted interaction between miR-532-3p and TXNIP validated by dual-luciferase reporter assay; C Binding relationship between miR-532-3p and TXNIP explored by RIP assay; D Expression of TXNIP in liver tissues of NAFLD patients analyzed by Western blot; E TXNIP expression in liver tissues of NAFLD rats assessed by Western blot; F effect of miR-532-3p overexpression on TXNIP levels determined by Western blot; data are represented as mean ± SD (n = 3). *P < 0.05

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European Journal of Medical Research

ISSN: 2047-783X

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