Fig. 9

circSOD2 inhibits NAFLD in vivo. A miR-532-3p expression in rat liver tissues analyzed by RT-qPCR; B expression of TXNIP and NLRP3 in rat liver tissues assessed by Western blot; C representative images of Oil Red O staining of rat liver tissues (40 × , 200 μm); D TUNEL staining for apoptosis in rat liver tissues (40 × ,100 μm); E levels of serum ALT, AST, TC, TG, and liver TNF-α, IL-1β, IL-6, MDA, and SOD in rats; F Western blot analysis of IL-1β, IL-18, and phosphorylated p65 protein expression in rat liver tissues; G IHC detection of GSDMD and cleaved caspase-1 positivity rates in rat liver tissues; Data are presented as mean  ± SD (n = 10) *P < 0.05.