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Table 3 The prognostic value of FNDC3B (Overall Survival) in subgroups of patients with pancreatic cancer

From: Identification of fibronectin type III domain containing 3B as a potential prognostic and therapeutic target for pancreatic cancer: a preliminary analysis

Characteristics

Total (N)

HR (95% CI)

P value

T stage

 T1 & T2

31

1.416 (0.433–4.635)

0.5435

 T3 & T4

145

1.468 (0.951–2.265)

0.0803

N stage

 N0

50

1.495 (0.593–3.768)

0.3873

 N1

123

1.078 (0.681–1.706)

0.7470

M stage

 M0

79

1.566 (0.860–2.854)

0.1470

 M1

5

–

–

Radiation therapy

 No

118

1.893 (1.176–3.046)

0.0096

 Yes

45

1.249 (0.476–3.276)

0.6381

Primary therapy outcome

 PD & SD

58

1.200 (0.673–2.138)

0.5306

 PR & CR

81

1.835 (0.906–3.717)

0.0912

Gender

 Female

80

1.239 (0.695–2.209)

0.4661

 Male

98

2.178 (1.222–3.883)

0.0064

Race

 White

157

1.760 (1.133–2.733)

0.0096

 Asian & Black or African American

17

0.894 (0.217–3.677)

0.8643

Age

 ≤ 65

93

2.376 (1.322–4.269)

0.0029

 > 65

85

1.186 (0.670–2.101)

0.5524

Residual tumor

 R0

107

1.494 (0.863–2.588)

0.1528

 R1 & R2

57

1.398 (0.711–2.748)

0.3227

Histologic grade

 G1 & G2

126

1.925 (1.162–3.189)

0.0099

 G3 & G4

50

1.193 (0.583–2.443)

0.6201

Anatomic neoplasm subdivision

 Head of pancreas

138

1.284 (0.828–1.991)

0.2604

 Other

40

4.631 (1.539–13.940)

0.0098

  1. Total patients’ number does not equal to 178 in all variates due to lack of patient’s information for some cases
  2. CR complete response, FNDC3B fibronectin type III domain containing 3B, G1: well-differentiated, G2: moderately-differentiated, G3: poorly-differentiated, G4: undifferentiated, M: metastasis, N: lymph node, PC pancreatic cancer, PR partial response, PD progressive disease, SD stable disease, T: tumor
  3. Bold values indicate that P < 0.05 which are statistically significant