Fig. 3From: Disordered GPR43/NLRP3 expression in peripheral leukocytes of patients with atrial fibrillation is associated with intestinal short chain fatty acids levelsRemarkable correlation between fecal SCFAs and the levels of GPR43 and NLRP3 mRNA in leukocytes. A Stack bar plot depicted the relative abundance (log 10) of fecal SCFAs, including acetic acid, propionic acid, butyric acid, isobutyric acid, isovaleric acid, valeric acid and caproic acid. B Heatmap presented the correlation between fecal SCFAs and the network presented the correlation between leukocyte GPR43 and NLRP3 mRNA and fecal SCFAs, respectively. Total SCFAs: acetic acid, propionic acid, butyric acid, isobutyric acid, isovaleric acid, valeric acid and caproic acid; SCFAs: acetic acid, propionic acid and butyric acid. Spearman’s correlation analysis; Red, positive correlation; green, negative correlation; red line, positive correlation; blue line, negative correlation; line width, the Spearman correlation coefficient; *P < 0.05; **P < 0.01. C, D Scatter plots of correlation between acetic acid and the levels of GPR43 (R = 0.34, P = 0.046) and NLRP3 (R = − 0.34, P = 0.049) mRNA in leukocytes. E Significantly negative correlation between GPR43 and NLRP3 mRNA expression in leukocytes (R = − 0.33, P = 0.024). Spearman’s correlation analysisBack to article page