Fig. 5

A prediction model based on leukocyte GPR43 and NLRP3 for AF. A Receiver operating curves (ROC) for leukocyte GPR43, NLRP3 mRNA expression and the GPR43–NLRP3 score. The area under the receiver operating curves (AUC values) were 0.69 for GPR43 (95% CI 0.54–0.82, P = 0.012), 0.78 for NLRP3 (95% CI 0.63–0.88, P < 0.001), 0.81 for the GRP43-NLRP3 score (95% CI 0.67–0.91, P < 0.001). B Higher GPR43–NLRP3 scores in AF patients than in controls. T-test, ***P < 0.001. C, D The GPR43–NLRP3 score was positively associated with LAD (R = 0.46, P = 0.002) and negatively associated with LVEF (R = − 0.35, P = 0.018). Spearman’s correlation analysis