Table 1 Description of features of all patients

N

24,402

17,081

7321

Time

58 [16, 83]

58 [16, 83]

58 [17, 83]

0.803

Age

 0–19 years

308 (1.3%)

211 (1.2%)

97 (1.3%)

0.781

 20–39 years

1972 (8.1%)

1389 (8.1%)

583 (8.0%)

 40–59 years

6450 (26%)

4490 (26%)

1960 (27%)

 60–79 years

11,702 (48%)

8227 (48%)

3475 (47%)

 80–100 years

3970 (16%)

2764 (16%)

1206 (16%)

Ann Arbor stage

 Stage I

5418 (22%)

3772 (22%)

1646 (22%)

0.908

 Stage II

5372 (22%)

3769 (22%)

1603 (22%)

 Stage III

5016 (21%)

3522 (21%)

1494 (20%)

 Stage IV

8596 (35%)

6018 (35%)

2578 (35%)

B symptoms

7959 (33%)

5547 (32%)

2412 (33%)

0.5

Chemotherapy

 With

22,728 (93%)

15,909 (93%)

6819 (93%)

1

 Without

1674 (6.9%)

1172 (6.9%)

502 (6.9%)

First primary tumor

19,747 (81%)

13,807 (81%)

5940 (81%)

0.6

Marital status

 Divorced

2023 (8.3%)

1384 (8.1%)

639 (8.7%)

0.381

 Married

13,727 (56%)

9577 (56%)

4150 (57%)

 Other

1151 (4.7%)

810 (4.7%)

341 (4.7%)

 Separated

226 (0.9%)

163 (1.0%)

63 (0.9%)

 Single

4324 (18%)

3061 (18%)

1263 (17%)

 Widowed

2951 (12%)

2086 (12%)

865 (12%)

Median household income

 < $50,000

3401 (14%)

2364 (14%)

1037 (14%)

0.767

 > $75,000

7138 (29%)

5011 (29%)

2127 (29%)

 $50,000–$74,999

13,863 (57%)

9706 (57%)

4157 (57%)

Number of malignancies

 > 1

6792 (28%)

4775 (28%)

2017 (28%)

0.529

 1

17,610 (72%)

12,306 (72%)

5304 (72%)

Place of residence

 Metropolitan

21,659 (89%)

15,168 (89%)

6491 (89%)

0.772

 Nonmetropolitan

2743 (11%)

1913 (11%)

830 (11%)

Primary site

 Digestive system

978 (4.0%)

684 (4.0%)

294 (4.0%)

0.166

 Intra-abdominal lymph nodes

1557 (6.4%)

1113 (6.5%)

444 (6.1%)

 Intrathoracic lymph nodes

655 (2.7%)

460 (2.7%)

195 (2.7%)

 Lymph nodes of axilla or arm

455 (1.9%)

321 (1.9%)

134 (1.8%)

 Lymph nodes of head, face and neck

1634 (6.7%)

1120 (6.6%)

514 (7.0%)

 Lymph nodes of inguinal region or leg

574 (2.4%)

380 (2.2%)

194 (2.6%)

 Lymph nodes of multiple regions

8045 (33%)

5688 (33%)

2357 (32%)

 Nervous system

6 (< 0.1%)

4 (< 0.1%)

2 (< 0.1%)

 Other

10,318 (42%)

7175 (42%)

3143 (43%)

 Pelvic lymph nodes

180 (0.7%)

136 (0.8%)

44 (0.6%)

Race

 Asian

2087 (8.6%)

1464 (8.6%)

623 (8.5%)

0.139

 Black

1744 (7.1%)

1260 (7.4%)

484 (6.6%)

 Other

224 (0.9%)

150 (0.9%)

74 (1.0%)

 White

20,347 (83%)

14,207 (83%)

6140 (84%)

Radiation

 With

5204 (21%)

3665 (21%)

1539 (21%)

0.458

 Without

19,198 (79%)

13,416 (79%)

5782 (79%)

Sex

 Female

10,480 (43%)

7305 (43%)

3175 (43%)

0.392

 Male

13,922 (57%)

9776 (57%)

4146 (57%)

Site

 Extra nodal

7050 (29%)

4910 (29%)

2140 (29%)

0.452

 Nodal

17,352 (71%)

12,171 (71%)

5181 (71%)

Surgery

 With

5252 (22%)

3657 (21%)

1595 (22%)

0.523

 Without

19,150 (78%)

13,424 (79%)

5726 (78%)

The sequence of systemic therapy and surgery

 No systemic therapy and/or surgery

19,384 (79%)

13,582 (80%)

5802 (79%)

0.878

 Other

27 (0.1%)

18 (0.1%)

9 (0.1%)

 Systemic therapy after surgery

4812 (20%)

3354 (20%)

1458 (20%)

 Systemic therapy before surgery

122 (0.5%)

89 (0.5%)

33 (0.5%)

 Systemic therapy both before and after surgery

57 (0.2%)

38 (0.2%)

19 (0.3%)

Treatment timing

 \(\le\) 1 month

11,114 (46%)

7803 (46%)

3311 (45%)

0.521

 > 1 month

13,288 (54%)

9278 (54%)

4010 (55%)

Status

 0

13,867 (57%)

9707 (57%)

4160 (57%)

1

 1

6459 (26%)

4521 (26%)

1938 (26%)

 2

4076 (17%)

2853 (17%)

1223 (17%)