Associations between Life’s Essential 8 and post-stroke depression and all-cause mortality among US adults

Table 4 Subgroup analysis of multi-variable adjusted association of LE8 score with the risk of PSD

Variable name	Non-PSD	PSD	p value	p for interaction
Age
20–59 years	Reference	0.95 (0.93,0.97)	< 0.001	0.70
60 years	Reference	0.95 (0.93,0.97)	< 0.001	0.70
Sex
Male	Reference	0.94 (0.92,0.96)	< 0.001	0.13
Female	Reference	0.96 (0.94,0.98)	< 0.001	0.13
Race
White	Reference	0.94 (0.93,0.96)	< 0.001	0.11
Black	Reference	0.98 (0.95,1.00)	0.06
Mexican American	Reference	0.97 (0.93,1.00)	0.08
Other	Reference	0.94 (0.90,0.98)	0.01
Education
Less than high school	Reference	0.97 (0.94,0.99)	0.02	0.48
High school	Reference	0.95 (0.93,0.97)	< 0.001
College or above	Reference	0.95 (0.92,0.97)	< 0.001
Marital
Married	Reference	0.95 (0.93,0.96)	< 0.001	0.68
Never married	Reference	0.95 (0.91,1.00)	0.04
Divorced	Reference	0.96 (0.94,0.98)	< 0.001
Poverty income ratio
≤ 1.30	Reference	0.96 (0.95,0.98)	< 0.001	0.15
1.30–3.49	Reference	0.95 (0.93,0.98)	0.001
≥ 3.50	Reference	0.92 (0.89,0.96)	< 0.001

Each stratification was adjusted for age, sex, race, education, marital and poverty income ratio
LE8 Life’s Essential 8, PSD post-stroke depression

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