Table 1 Baseline characteristics of the two groups
Variables | Original cohort | Weighted cohort | ||||
|---|---|---|---|---|---|---|
Survival group (n = 302) | Non-survival group (n = 496) | P-value | Survival group (n = 290) | Non-survival group (n = 511) | P-value | |
Age (year) | 62.52 ± 16.59 | 66.51 ± 17.80 | 0.002 | 62.89 ± 16.14 | 68.06 ± 17.67 | < 0.001 |
Sex, male, n (%) | 196 (64.90) | 304 (61.29) | 0.307 | 181.20 (62.50) | 323.30 (63.20) | < 0.001 |
SOFA score | 9.00 (5.00, 12.00) | 11.00 (8.00, 14.00) | < 0.001 | 9.00 (5.00, 12.00) | 10.72 (7.00, 13.00) | < 0.001 |
Serum calcium (mg/L) | 8.33 ± 1.08 | 8.28 ± 1.60 | 0.643 | 8.31 ± 1.06 | 8.22 ± 1.50 | 0.393 |
Albumin (g/dL) | 3.40 ± 0.70 | 3.04 ± 0.75 | < 0.001 | 3.37 ± 0.71 | 3.05 ± 0.72 | < 0.001 |
ACC (mg/dl) | 8.81 ± 1.01 | 9.05 ± 1.63 | 0.021 | 8.81 ± 0.96 | 8.98 ± 1.50 | 0.066 |
WBC (× 109/L) | 12.20 (8.60, 17.40) | 13.00 (8.65, 18.90) | 0.309 | 12.20 (8.52, 17.00) | 13.30 (9.20, 19.80) | 0.086 |
Hemoglobin (g/L) | 121.18 ± 27.46 | 115.16 ± 27.94 | 0.003 | 119.58 ± 30.15 | 113.27 ± 28.04 | 0.042 |
Platelet (× 109/L) | 209.50 (158.00, 269.00) | 200.50 (139.50, 274.00) | 0.348 | 209.00 (158.00, 267.00) | 205.00 (142.00, 286.72) | 0.895 |
RDW (%) | 14.61 ± 2.25 | 15.34 ± 2.44 | < 0.001 | 14.75 ± 2.44 | 15.53 ± 2.46 | 0.005 |
MCV (fL) | 92.60 ± 7.53 | 94.29 ± 8.35 | 0.004 | 92.67 ± 7.70 | 94.54 ± 8.39 | 0.010 |
Anion gap (mmol/L) | 17.65 ± 5.29 | 20.09 ± 6.43 | < 0.001 | 17.58 ± 5.37 | 20.23 ± 6.81 | < 0.001 |
BUN (mg/dL) | 7.48 (4.98, 11.39) | 9.61 (6.05, 16.38) | < 0.001 | 7.48 (5.28, 11.75) | 9.97 (6.41, 17.44) | < 0.001 |
creatinine (umol/L) | 106.08 (79.56, 150.28) | 132.60 (88.40, 194.48) | < 0.001 | 106.08 (79.56, 159.12) | 132.60 (97.24, 203.32) | 0.001 |
ALT (U/L) | 53.00 (27.00, 139.00) | 72.50 (29.00, 219.50) | 0.004 | 52.00 (26.00, 140.89) | 63.00 (29.00, 183.98) | 0.114 |
AST (U/L) | 81.00 (40.00, 191.00) | 119.50 (47.50, 373.00) | < 0.001 | 81.00 (39.00, 195.66) | 102.00 (41.00, 322.10) | 0.038 |
Glucose (mmol/L) | 9.11 (6.89, 13.00) | 9.47 (6.97, 14.22) | 0.356 | 9.28 (7.17, 13.05) | 9.00 (6.65, 13.85) | 0.697 |
Bilirubin (umol/L) | 10.26 (6.84, 15.39) | 10.26 (6.84, 18.81) | 0.312 | 10.26 (6.84, 15.39) | 10.26 (6.84, 18.81) | 0.291 |
Potassium (mmol/L) | 4.49 ± 1.18 | 4.56 ± 1.09 | 0.436 | 4.50 ± 1.16 | 4.56 ± 1.09 | 0.553 |
Phosphate (mmol/L) | 1.43 ± 0.65 | 1.70 ± 0.82 | < 0.001 | 1.46 ± 0.67 | 1.69 ± 0.83 | 0.002 |
Transthoracic echocardiography, n (%) | 128 (42.38) | 169 (34.07) | 0.018 | 114.10 (39.30) | 175.20 (34.30) | 0.200 |
Norepinephrine, n (%) | 170 (56.29) | 355 (71.57) | < 0.001 | 162.70 (56.10) | 350.10 (68.50) | 0.005 |
Dobutamine, n (%) | 15 (4.97) | 35 (7.06) | 0.237 | 15.80 (5.50) | 32.20 (6.30) | 0.651 |
MV, n (%) | 259 (85.76) | 441 (88.91) | 0.189 | 248.40 (85.60) | 437.50 (85.60) | 0.986 |
CRRT, n (%) | 26 (8.61) | 58 (11.69) | 0.169 | 30.0 (10.30) | 53.8 (10.50) | 0.956 |
IABP, n (%) | 16 (5.30) | 23 (4.64) | 0.674 | 17.50 (6.00) | 22.40 (4.40) | 0.337 |
Defibrillation, n (%) | 17 (5.63) | 21 (4.23) | 0.369 | 17.10 (5.90) | 22.40 (4.40) | 0.380 |
Comorbidities, n (%) | ||||||
Hypertension | 119 (39.40) | 184 (37.10) | 0.515 | 111.10 (38.30) | 187.90 (36.70) | 0.693 |
Diabetes | 93 (30.79) | 152 (30.65) | 0.965 | 100.90 (34.80) | 155.20 (30.40) | 0.268 |
AKI | 246 (81.46) | 411 (82.86) | 0.614 | 239.90 (82.70) | 431.30 (84.4) | 0.555 |
Chronic pulmonary disease | 80 (26.49) | 120 (24.19) | 0.468 | 76.30 (26.30) | 119.70 (23.40) | 0.408 |
Pulmonary embolism | 18 (5.96) | 22 (4.44) | 0.338 | 16.20 (5.60) | 27.10 (5.30) | 0.874 |
DVT | 11 (3.64) | 19 (3.83) | 0.892 | 13.10 (4.50) | 26.00 (5.10) | 0.772 |
VF | 70 (23.18) | 69 (13.91) | 0.001 | 65.10 (22.40) | 67.40 (13.20) | 0.002 |
Congestive heart failure | 134 (44.37) | 165 (33.27) | 0.002 | 131.90 (45.50) | 186.00 (36.40) | 0.037 |
Cerebrovascular disease | 32 (10.60) | 84 (16.94) | 0.014 | 31.40 (10.80) | 82.80 (16.20) | 0.051 |
Malignant tumor | 26 (8.61) | 68 (13.71) | 0.030 | 23.20 (8.00) | 79.50 (15.50) | 0.014 |
AMI | 69 (22.85) | 103 (20.77) | 0.488 | 65.20 (22.50) | 101.10 (19.80) | 0.398 |
Cardiogenic shock | 55 (18.21) | 88 (17.74) | 0.867 | 52.10 (18.00) | 92.90 (18.20) | 0.949 |
ICU LOS (d) | 4.55 (2.29, 8.90) | 2.66 (1.06, 6.32) | < 0.001 | 4.55 (2.32, 8.69) | 2.65 (1.07, 6.15) | < 0.001 |