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  1. Research

    The impact of mild induced hypothermia on the rate of transfusion and the mortality in severely injured patients: a retrospective multi-centre study

    Although under discussion, induced hypothermia (IH) is an established therapy for patients with cardiac arrest or traumatic brain injuries. The influences on coagulopathy and bleeding tendency in severely inju...

    Kai Oliver Jensen, Leonhard Held, Andrea Kraus, Frank Hildebrand, Philipp Mommsen, Ladislav Mica, Guido A. Wanner, Peter Steiger, Rudolf M. Moos, Hans-Peter Simmen and Kai Sprengel

    European Journal of Medical Research 2016 21:37

    Published on: 6 October 2016

  2. Case report

    Pseudoaneurysm of the anterior tibial artery after interlocking tibial nailing: an unexpected complication

    Anterior tibial pseudoaneurysm is a rare complication after interlocking screw insertion in tibial nailing. We present the case of a 28-year-old male patient with this complication with a 6-week delay after ti...

    F. Greve, M. Crönlein, M. Beirer, C. Kirchhoff, P. Biberthaler and K. F. Braun

    European Journal of Medical Research 2016 21:36

    Published on: 29 September 2016

  3. Research

    Unplanned readmissions in younger and older adult patients: the role of healthcare-related adverse events

    Readmissions are a burden for patients and increase healthcare costs. In Europe, factors associated with readmissions have not yet been extensively investigated. This study aimed to discover factors associated...

    Fabienne J. H. Magdelijns, Larissa Schepers, Evelien Pijpers, Coen D. A. Stehouwer and Patricia M. Stassen

    European Journal of Medical Research 2016 21:35

    Published on: 15 September 2016

  4. Research

    Molecular analysis of the CTSK gene in a cohort of 33 Brazilian families with pycnodysostosis from a cluster in a Brazilian Northeast region

    Pycnodysostosis is an autosomal recessive skeletal dysplasia, the prevalence of which is estimated to be low (1 per million). Nevertheless, in recent years we have found 27 affected individuals from 22 familie...

    Thaís Fenz Araujo, Erlane Marques Ribeiro, Anderson Pontes Arruda, Carolina Araujo Moreno, Paula Frassinetti Vasconcelos de Medeiros, Renata Moldenhauer Minillo, Débora Gusmão Melo, Chong Ae Kim, Maria Juliana Rodovalho Doriqui, Têmis Maria Felix, Rodrigo Ambrosio Fock and Denise Pontes Cavalcanti

    European Journal of Medical Research 2016 21:33

    Published on: 24 August 2016

  5. Research

    Waiting time for radiation therapy after breast-conserving surgery in early breast cancer: a retrospective analysis of local relapse and distant metastases in 615 patients

    Postoperative radiotherapy after breast-conserving surgery (BCS) is the standard in the management of breast cancer. The optimal timing for starting postoperative radiation therapy has not yet been well define...

    Raffaella Caponio, Maria Paola Ciliberti, Giusi Graziano, Rocco Necchia, Giovanni Scognamillo, Antonio Pascali, Sabino Bonaduce, Anna Milella, Gabriele Matichecchia, Cristian Cristofaro, Davide Di Fatta, Pasquale Tamborra and Marco Lioce

    European Journal of Medical Research 2016 21:32

    Published on: 11 August 2016

  6. Review

    Stem cell procedures in arthroscopic surgery

    The stem cell as the building block necessary for tissue reparation and homeostasis plays a major role in regenerative medicine. Their unique property of being pluripotent, able to control immune process and e...

    Felix Dyrna, Elmar Herbst, Alexander Hoberman, Andreas B. Imhoff and Andreas Schmitt

    European Journal of Medical Research 2016 21:29

    Published on: 13 July 2016

  7. Research

    Evaluation and clinical significance of cyclin-dependent kinase5 expression in cervical lesions: a clinical research study in Guangxi, China

    Studies have been reported that cyclin-dependent kinase5 (CDK5) was associated with the development of several cancers. However, the relationship between CDK5 level and clinicopathological factors is still poo...

    Deng-Hua Pan, Mei-Lin Zhu, Xiao-Miao Lin, Xing-Gu Lin, Rong-Quan He, Yan-Xin Ling, Shi-Tao Su, Madushi Mihiranganee Wickramaarachchi, Yi-Wu Dang, Kang-Lai Wei and Gang Chen

    European Journal of Medical Research 2016 21:28

    Published on: 12 July 2016

  8. Research

    Modified Hughes procedure for reconstruction of large full-thickness lower eyelid defects following tumor resection

    Tarsoconjunctival flap advancement, or the Hughes procedure, is among the techniques of choice for reconstructing full-thickness lower eyelid defects so as to restore normal anatomy and function with the best ...

    Ahmed M. Hishmi, Konrad R. Koch, Mario Matthaei, Edwin Bölke, Claus Cursiefen and Ludwig M. Heindl

    European Journal of Medical Research 2016 21:27

    Published on: 30 June 2016

  9. Research

    sMICA as novel and early predictors for acute myocardial infarction

    MHC class I polypeptide-related chain A (MICA) molecule is induced in response to viral infection, various types of stress, such as endoplasmic reticulum stress, and ischemia or/and reperfusion, by which MICA ...

    Cunyu Fu, Yunxiang Shi and Zongqin Yao

    European Journal of Medical Research 2016 21:25

    Published on: 16 June 2016

  10. Review

    Breast reconstruction after neoadjuvant radio chemotherapy: review and personal technique IDEAL concept

    Neoadjuvant radio chemotherapy and immediate reconstruction for breast cancer are still under debate. But there are recent abstracts and articles which show that neoadjuvant radio chemotherapy is feasible and ...

    Carolin Nestle-Krämling, Edwin Bölke, Wilfried Budach and Christoph Andree

    European Journal of Medical Research 2016 21:24

    Published on: 10 June 2016

    The Erratum to this article has been published in European Journal of Medical Research 2016 21:30

  11. Research

    Serum prolactin as a biomarker for the study of intracerebral dopamine effect in adult patients with phenylketonuria: a cross-sectional monocentric study

    It has been previously postulated that high phenylalanine (Phe) might disturb intracerebral dopamine production, which is the main regulator of prolactin secretion in the pituitary gland. Previously, various a...

    Eszter Juhász, Erika Kiss, Erika Simonova, Attila Patócs and Peter Reismann

    European Journal of Medical Research 2016 21:22

    Published on: 11 May 2016

  12. Review

    Longitudinal strain bull’s eye plot patterns in patients with cardiomyopathy and concentric left ventricular hypertrophy

    Despite substantial advances in the imaging techniques and pathophysiological understanding over the last decades, identification of the underlying causes of left ventricular hypertrophy by means of echocardio...

    Dan Liu, Kai Hu, Peter Nordbeck, Georg Ertl, Stefan Störk and Frank Weidemann

    European Journal of Medical Research 2016 21:21

    Published on: 10 May 2016

  13. Research

    The value of initial cavitation to predict re-treatment with pulmonary tuberculosis

    Pulmonary cavitation is the classic hallmark of pulmonary tuberculosis (PTB) and is the site of very high mycobacterial burden associated with antimycobacterial drug resistance and treatment failure. The objec...

    Qiusheng Huang, Yongmei Yin, Shougang Kuai, Yan Yan, Jun Liu, YingYing Zhang, Zhongbao Shan, Lan Gu, Hao Pei and Jun Wang

    European Journal of Medical Research 2016 21:20

    Published on: 6 May 2016

  14. Case report

    A novel LAMB2 gene mutation associated with a severe phenotype in a neonate with Pierson syndrome

    Pierson syndrome (PS) is a rare autosomal recessive disorder, caused by mutations in the laminin β2 (LAMB2) gene. It is characterized by congenital nephrotic syndrome, microcoria, and neurodevelopmental defici...

    Boutaina Zemrani, François Cachat, Olivier Bonny, Eric Giannoni, Jacques Durig, Florence Fellmann and Hassib Chehade

    European Journal of Medical Research 2016 21:19

    Published on: 30 April 2016

  15. Research

    Clinical application of computed tomography-guided 125I seed interstitial implantation for head and neck cancer patients with unmanageable cervical lymph node metastases

    To assess clinical application of computed tomography (CT)-guided 125I seed implantation for patients who cannot endure or unwillingly receive repeated surgery, chemotherapy, or radiotherapy for unmanageable cerv...

    Hai Huang, Shaonian Xu, Fusheng Li, Zhenguang Du and Liang Wang

    European Journal of Medical Research 2016 21:18

    Published on: 27 April 2016

  16. Research

    Association of CYP1A1, GSTM1 and GSTT1 gene polymorphisms with risk of non-small cell lung cancer in Andhra Pradesh region of South India

    Lung cancer is one of the most preventable causes of death globally both in developed and developing countries. Although it is well established that smokers develop lung cancer, there are some smokers who are ...

    Vidyullatha Peddireddy, Siva Prasad Badabagni, Sandhya Devi Gundimeda, Vasudha Mamidipudi, Pardhanandana Reddy Penagaluru and Hema Prasad Mundluru

    European Journal of Medical Research 2016 21:17

    Published on: 18 April 2016

  17. Research

    Hepatitis B and human immunodeficiency virus co-infection among pregnant women in resource-limited high endemic setting, Addis Ababa, Ethiopia: implications for prevention and control measures

    Hepatitis, a highly contagious viral infection, is one of the leading killer diseases globally caused by hepatitis virus. Among the existing viral causes for hepatic failure, hepatitis B virus (HBV) plays a si...

    Zelalem Desalegn, Liya Wassie, Habtamu Bedimo Beyene, Adane Mihret and Yehenew A. Ebstie

    European Journal of Medical Research 2016 21:16

    Published on: 14 April 2016

  18. Research

    Reduction and stabilization of radial neck fractures by intramedullary pinning: a technique not only for children

    Isolated radial neck fractures occur only in rare cases. The majority of cases are non-displaced or minimally displaced and can be treated conservatively. Conservative treatment, however, might result in secon...

    G. H. Sandmann, M. Crönlein, M. Neumaier, M. Beirer, A. Buchholz, U. Stöckle, P. Biberthaler and S. Siebenlist

    European Journal of Medical Research 2016 21:15

    Published on: 12 April 2016

  19. Review

    Vitamin D and airway infections: a European perspective

    Vitamin D has immuno-modulatory properties, and deficient levels of circulating 25-hydroxyvitamin D (<30 nmol/l) may contribute to increased risk of infectious illnesses. This narrative review summarises data ...

    Armin Zittermann, Stefan Pilz, Harald Hoffmann and Winfried März

    European Journal of Medical Research 2016 21:14

    Published on: 24 March 2016

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