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  1. Research

    The need for maximal sterile barrier precaution in routine interventional coronary procedures; microbiology analysis

    Maximal sterile barrier precautions (MSBP) including head coverings and face masks are advocated for use in invasive procedures, including coronary interventions. The rationale for MSBP assumes it is an obliga...

    Avi Peretz, Fabio Kuzniec, Diab Ganem, Nabeeh Salman, Dahud Qarawani and Offer Amir

    European Journal of Medical Research 2016 21:45

    Published on: 10 November 2016

  2. Research

    Is it time to rebalance the case mix? A portfolio analysis of direct catheterization laboratory costs over a 5-year period

    Cardiac catheterization laboratories (CLL) have continued to function as profit centers for hospitals. Due to a high percentage of material and labor costs, they are natural targets for process improvement. Ou...

    Gunnar Plehn, Thomas Butz, Petra Maagh, Ahmet Oernek, Axel Meissner and Natalie Plehn

    European Journal of Medical Research 2016 21:44

    Published on: 3 November 2016

  3. Research

    C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing

    Recent studies were able to demonstrate involvement of the complement cascade in bone biology. Further studies analyzed the role of complement in traumatic injuries and demonstrated negative effects after exce...

    Christian Ehrnthaller, Markus Huber-Lang, Anna Kovtun, Anna Elise Rapp, Julia Kemmler, Florian Gebhard and Anita Ignatius

    European Journal of Medical Research 2016 21:42

    Published on: 26 October 2016

  4. Research

    Incidence of left atrial abnormalities under treatment with dabigatran, rivaroxaban, and vitamin K antagonists

    Non-vitamin K antagonist oral anticoagulants (NOACs) such as dabigatran or rivaroxaban are alternatives to vitamin K antagonists (VKAs) for prevention of stroke and systemic embolism in patients with atrial fi...

    Stefan Reers, Tolga Agdirlioglu, Michael Kellner, Matthias Borowski, Holger Thiele, Johannes Waltenberger and Michael Reppel

    European Journal of Medical Research 2016 21:41

    Published on: 21 October 2016

  5. Research

    Resuscitation with polymeric plasma substitutes is permissive for systemic inflammatory response syndrome and sepsis in multiply injured patients: a retrospective cohort study

    Multiple trauma is often accompanied by systemic inflammatory response syndrome (SIRS). The aim of this study was to investigate the impact of polymeric plasma substitutes on the development of SIRS or sepsis.

    Kai Sprengel, Hanspeter Simmen, Clément M. L. Werner, Simon Sulser, Michael Plecko, Catharina Keller and Ladislav Mica

    European Journal of Medical Research 2016 21:39

    Published on: 13 October 2016

  6. Case report

    Long term disease free survival with multimodal therapy in small cell bladder cancer

    Small cell bladder cancer (SCBC) is an aggressive subtype accounting for less than 1 % of all bladder malignancies associated with rapid progression, early metastases formation and high mortality rates.

    Isabel Heidegger, Gennadi Tulchiner, Georg Schäfer, Wolfgang Horninger and Renate Pichler

    European Journal of Medical Research 2016 21:40

    Published on: 13 October 2016

  7. Research

    Cytokine and human leukocyte antigen (HLA) profile for graft-versus-host disease (GVHD) after organ transplantation

    Graft-versus-host disease (GVHD) after liver and kidney transplantation has high mortality and causes diagnostic challenges. This study aims to describe the cytokine and human leukocyte antigen (HLA) profile i...

    Xinhua Chen, Xueqin Meng, Yuning Xu, Haiyang Xie, Shengyong Yin, Hongchun Li, Liming Wu and Shusen Zheng

    European Journal of Medical Research 2016 21:38

    Published on: 12 October 2016

  8. Research

    The impact of mild induced hypothermia on the rate of transfusion and the mortality in severely injured patients: a retrospective multi-centre study

    Although under discussion, induced hypothermia (IH) is an established therapy for patients with cardiac arrest or traumatic brain injuries. The influences on coagulopathy and bleeding tendency in severely inju...

    Kai Oliver Jensen, Leonhard Held, Andrea Kraus, Frank Hildebrand, Philipp Mommsen, Ladislav Mica, Guido A. Wanner, Peter Steiger, Rudolf M. Moos, Hans-Peter Simmen and Kai Sprengel

    European Journal of Medical Research 2016 21:37

    Published on: 6 October 2016

  9. Case report

    Pseudoaneurysm of the anterior tibial artery after interlocking tibial nailing: an unexpected complication

    Anterior tibial pseudoaneurysm is a rare complication after interlocking screw insertion in tibial nailing. We present the case of a 28-year-old male patient with this complication with a 6-week delay after ti...

    F. Greve, M. Crönlein, M. Beirer, C. Kirchhoff, P. Biberthaler and K. F. Braun

    European Journal of Medical Research 2016 21:36

    Published on: 29 September 2016

  10. Research

    Unplanned readmissions in younger and older adult patients: the role of healthcare-related adverse events

    Readmissions are a burden for patients and increase healthcare costs. In Europe, factors associated with readmissions have not yet been extensively investigated. This study aimed to discover factors associated...

    Fabienne J. H. Magdelijns, Larissa Schepers, Evelien Pijpers, Coen D. A. Stehouwer and Patricia M. Stassen

    European Journal of Medical Research 2016 21:35

    Published on: 15 September 2016

  11. Research

    Molecular analysis of the CTSK gene in a cohort of 33 Brazilian families with pycnodysostosis from a cluster in a Brazilian Northeast region

    Pycnodysostosis is an autosomal recessive skeletal dysplasia, the prevalence of which is estimated to be low (1 per million). Nevertheless, in recent years we have found 27 affected individuals from 22 familie...

    Thaís Fenz Araujo, Erlane Marques Ribeiro, Anderson Pontes Arruda, Carolina Araujo Moreno, Paula Frassinetti Vasconcelos de Medeiros, Renata Moldenhauer Minillo, Débora Gusmão Melo, Chong Ae Kim, Maria Juliana Rodovalho Doriqui, Têmis Maria Felix, Rodrigo Ambrosio Fock and Denise Pontes Cavalcanti

    European Journal of Medical Research 2016 21:33

    Published on: 24 August 2016

  12. Research

    Waiting time for radiation therapy after breast-conserving surgery in early breast cancer: a retrospective analysis of local relapse and distant metastases in 615 patients

    Postoperative radiotherapy after breast-conserving surgery (BCS) is the standard in the management of breast cancer. The optimal timing for starting postoperative radiation therapy has not yet been well define...

    Raffaella Caponio, Maria Paola Ciliberti, Giusi Graziano, Rocco Necchia, Giovanni Scognamillo, Antonio Pascali, Sabino Bonaduce, Anna Milella, Gabriele Matichecchia, Cristian Cristofaro, Davide Di Fatta, Pasquale Tamborra and Marco Lioce

    European Journal of Medical Research 2016 21:32

    Published on: 11 August 2016

  13. Review

    Stem cell procedures in arthroscopic surgery

    The stem cell as the building block necessary for tissue reparation and homeostasis plays a major role in regenerative medicine. Their unique property of being pluripotent, able to control immune process and e...

    Felix Dyrna, Elmar Herbst, Alexander Hoberman, Andreas B. Imhoff and Andreas Schmitt

    European Journal of Medical Research 2016 21:29

    Published on: 13 July 2016

  14. Research

    Evaluation and clinical significance of cyclin-dependent kinase5 expression in cervical lesions: a clinical research study in Guangxi, China

    Studies have been reported that cyclin-dependent kinase5 (CDK5) was associated with the development of several cancers. However, the relationship between CDK5 level and clinicopathological factors is still poo...

    Deng-Hua Pan, Mei-Lin Zhu, Xiao-Miao Lin, Xing-Gu Lin, Rong-Quan He, Yan-Xin Ling, Shi-Tao Su, Madushi Mihiranganee Wickramaarachchi, Yi-Wu Dang, Kang-Lai Wei and Gang Chen

    European Journal of Medical Research 2016 21:28

    Published on: 12 July 2016

  15. Research

    Modified Hughes procedure for reconstruction of large full-thickness lower eyelid defects following tumor resection

    Tarsoconjunctival flap advancement, or the Hughes procedure, is among the techniques of choice for reconstructing full-thickness lower eyelid defects so as to restore normal anatomy and function with the best ...

    Ahmed M. Hishmi, Konrad R. Koch, Mario Matthaei, Edwin Bölke, Claus Cursiefen and Ludwig M. Heindl

    European Journal of Medical Research 2016 21:27

    Published on: 30 June 2016

  16. Research

    sMICA as novel and early predictors for acute myocardial infarction

    MHC class I polypeptide-related chain A (MICA) molecule is induced in response to viral infection, various types of stress, such as endoplasmic reticulum stress, and ischemia or/and reperfusion, by which MICA ...

    Cunyu Fu, Yunxiang Shi and Zongqin Yao

    European Journal of Medical Research 2016 21:25

    Published on: 16 June 2016

  17. Review

    Breast reconstruction after neoadjuvant radio chemotherapy: review and personal technique IDEAL concept

    Neoadjuvant radio chemotherapy and immediate reconstruction for breast cancer are still under debate. But there are recent abstracts and articles which show that neoadjuvant radio chemotherapy is feasible and ...

    Carolin Nestle-Krämling, Edwin Bölke, Wilfried Budach and Christoph Andree

    European Journal of Medical Research 2016 21:24

    Published on: 10 June 2016

    The Erratum to this article has been published in European Journal of Medical Research 2016 21:30

  18. Research

    Serum prolactin as a biomarker for the study of intracerebral dopamine effect in adult patients with phenylketonuria: a cross-sectional monocentric study

    It has been previously postulated that high phenylalanine (Phe) might disturb intracerebral dopamine production, which is the main regulator of prolactin secretion in the pituitary gland. Previously, various a...

    Eszter Juhász, Erika Kiss, Erika Simonova, Attila Patócs and Peter Reismann

    European Journal of Medical Research 2016 21:22

    Published on: 11 May 2016

  19. Review

    Longitudinal strain bull’s eye plot patterns in patients with cardiomyopathy and concentric left ventricular hypertrophy

    Despite substantial advances in the imaging techniques and pathophysiological understanding over the last decades, identification of the underlying causes of left ventricular hypertrophy by means of echocardio...

    Dan Liu, Kai Hu, Peter Nordbeck, Georg Ertl, Stefan Störk and Frank Weidemann

    European Journal of Medical Research 2016 21:21

    Published on: 10 May 2016

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