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Table 1 Patient characteristics in both study groups and average dosages during run-in phase and treatment phase in both groups

From: Levo-α-acetylmethadol (LAAM) induced QTc-prolongation - results from a controlled clinical trial

Treatment Group

Methadone (METH)

LAAM

Total number (n)

22

31

Gender

12 F/10 M

11 F/20 M

Age (avg)

31.0 yrs

27.9 yrs

Average dosage during run-in period (METH in both groups)

72.0 ± 25.5 mg daily

73.5 ± 25.7 mg daily

Average dosage during treatment phase

69 ± 27.6 mg METH

Mon & Wed

Fri

  

89.6 ± 32.4 mg LAAM

109.7 ± 39.5 mg LAAM

  

equiv. to 68.9 ± 24.9 mg METH*

equiv. to 68.6 ± 24.7 mg METH*

  1. *For better comparability, METH equivalents are shown in the LAAM groups assuming a factor of 1.3 (Monday & Wednesday) and 1.6 (Friday).