Figure 3From: Estrogen exposure, obesity and thyroid disease in women with severe pulmonary hypertension Schematic illustrating the potential interactions of pathobiologically relevant risk factos which may contribute to severe angioproliferative pulmonary arterial hypertension. Hypothetically, autoimmunity and chronic inflammation interact via thyroid disease, estrogen and obesity. VEGF = vascular endothelial growth factor, Bcl-2 = antiapoptotic B-cell lymphoma protein.Back to article page