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Table 1 Synopsis of GFR, renal histology and immunohistochemistry

From: Renal phenotype of Et-1 transgenic mice is modulated by androgens

Parameter

ET

ET+CAS

GFR (ml/min)

0.29 ± 0.05

0.37 ± 0.02

Protein Excretion (mg/24 h)

30 ± 2.6

5+/0.4*

Interstitial Fibrosis (%)

17.8 ± 1.9

14.6 ± 1.8

Media/Lumen-Ratio

2.0 ± 0.3

2.0 ± 0.3

CD8+cells/10000 cells

1987 ± 329

2352 ± 397

Macrophages/10000 cells

3552 ± 396

3446 ± 26

  1. All values are given as means ± SEM.*: p < 0.05 vs. ET