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Table 2 Biochemical markers and characteristics (mean ± SD) of bone metabolism of the male HIV-1 infected patients with hypogonadism (group I); (significance between HIV-1 infected men of group I or II and controls * p < 0.05) (significance between hypogonadal and eugonadal patients # p < 0.05)

From: Bone mineral density in human immunodeficiency virus-1 infected men with hypogonadism prior to highly-active-antiretroviral-therapy (HAART)

Parameter

Group I

(n = 32)

Group II

(n = 48)

Group III

(n = 20)

Range

 

HIV-1

Hypogonadism

HIV-1

Eugonadism

male controls

 

Serum Ca [mmol/l]

2.10 ± 0.107 *

2.21 ± 0.1

2.6 ± 0.23

2.20-2.65 [mmol/l]

Serum D 1,25(OH2)D [pg/ml]

27.9 ± 9.7 *

31.5 ± 7.5 *

67.45 ± 4.25

44-74 [pg/ml]

Serum D 25(OH)D [ng/ml]

24.3 ± 10.3 *#

46.7 ± 14.1 *

69.5 ± 13.5

8-80 [ng/ml]

PTH [pg/ml]

19.6 ± 8.9 *

28.5 ± 5.2 *

37.8 ± 4.8

10-65 [pg/ml]

Osteocalcin [ng/ml]

2.35 ± 0.57 * #

3.58 ± 0.53

3.6 ± 0.39

2.0-6.5 [ng/ml]

Creatinine [mg/dl]

0.89 ± 0.1

0.99 ± 0.14

0.87 ± 0.15

0.68-1.09 mg/dl

Albumine [g/l]

38.9 ± 6.2

41.3 ± 5.7

46.5 ± 3.7

35.8-50.6 [g/l]

Crosslinks [nmol/pyd/mmol Crea]

79.0 ± 11.7 *#

65.71 ± 10.2

31.5 ± 6.2

< 50

Urinary Ca [mmol/24 h]

7.72 ± 0.75 *#

4.47 ± 0.69

1.07 ± 0.31

< 6.2 [mmol/l]