Table 1 Microcirculatory parameters of the 4 different treatment groups at predefined points in time
From: Effect of fenofibrate on microcirculation and wound healing in healthy and diabetic mice
Parameter | day | ndf | ndnf | dbf | dbnf |
|---|---|---|---|---|---|
FCD (in cm/cm2) | 0 | 187.2 Ā± 18.2 | 199.0 Ā± 11.4 | 190.8 Ā± 14.1 | 199.5 Ā± 8.7 |
| Ā | 3 | 215.5 Ā± 16.6 | 210.8 Ā± 15.8 | 201.9 Ā± 12.7 | 211.0 Ā± 10.3 |
| Ā | 7 | 229.5 Ā± 14.5X | 222.1 Ā± 13.9X | 212.0 Ā± 10.9X | 215.8 Ā± 6.8X |
| Ā | 14 | 214.5 Ā± 19.5 | 209.4 Ā± 8.9 | 205.4 Ā± 10.6 | 208.1 Ā± 9.4 |
| Ā | 21 | 195.1 Ā± 14.6 | 202.4 Ā± 11.6 | 195.1 Ā± 12.0 | 198.3 Ā± 9.6 |
Diameter of arterioles (mm) | 0 | 41.0 Ā± 12.3 | 43.5 Ā± 8.3 | 37.7 Ā± 2.9 | 42.0 Ā± 6.6 |
| Ā | 3 | 41.0 Ā± 9.2 | 45.6 Ā± 10.5 | 45.5 Ā± 3.8X | 44.2 Ā± 7.8 |
| Ā | 7 | 40.9 Ā± 8.1 | 46.6 Ā± 10.3 | 41.6 Ā± 2.5 | 45.5 Ā± 5.0 |
| Ā | 14 | 39.6 Ā± 10.4 | 45.1 Ā± 10.0 | 40.2 Ā± 2.9 | 42.7 Ā± 5.4 |
| Ā | 21 | 42.8 Ā± 12.8 | 43.4 Ā± 9.6 | 40.1 Ā± 2.4 | 42.0 Ā± 6.3 |
Diameter of venules (mm) | 0 | 82.8 Ā± 18.3 | 82.8 Ā± 12.1 | 83.9 Ā± 7.8 | 78.5 Ā± 10.3 |
| Ā | 3 | 85.5 Ā± 22.3 | 85.8 Ā± 15.4 | 94.7 Ā± 8.1* | 81.1 Ā± 13.9 |
| Ā | 7 | 82.4 Ā± 19.6 | 83.6 Ā± 16.3 | 90.3 Ā± 8.4 | 76.7 Ā± 13.0 |
| Ā | 14 | 83.3 Ā± 17.1 | 83.9 Ā± 13.3 | 86.1 Ā± 8.2 | 75.6 Ā± 11.2 |
| Ā | 21 | 80.8 Ā± 20.2 | 81.7 Ā± 12.2 | 85.0 Ā± 7.8 | 77.1 Ā± 9.7 |
Rolling leukocytes (n/100 mm/20 sec) | 0 | 11.2 Ā± 2.1 | 12.0 Ā± 3.1 | 12.5 Ā± 2.0 | 13.0 Ā± 1.5 |
| Ā | 3 | 14.2 Ā± 1.9X | 15.5 Ā± 2.5X | 15.4 Ā± 1.4X | 16.0 Ā± 1.1X |
| Ā | 7 | 11.8 Ā± 1.7 | 13.1 Ā± 1.9 | 12.7 Ā± 1.2 | 13.2 Ā± 1.5 |
| Ā | 14 | 11.5 Ā± 1.8 | 11.6 Ā± 2.7 | 11.9 Ā± 0.9 | 12.1 Ā± 1.3 |
| Ā | 21 | 11.0 Ā± 1.5 | 11.6 Ā± 2.4 | 12.1 Ā± 0.9 | 12.0 Ā± 0.9 |
Sticky leukocytes (n/100 mm/20 sec) | 0 | 3.1 Ā± 0.8 | 3.6 Ā± 1.2 | 4.0 Ā± 1.2 | 3.8 Ā± 0.7 |
| Ā | 3 | 4.9 Ā± 1.4X | 5.9 Ā± 0.9X | 5.4 Ā± 1.1X | 5.3 Ā± 1.0X |
| Ā | 7 | 4.8 Ā± 0.8X | 6.1 Ā± 1.2X | 4.6 Ā± 0.8X | 5.2 Ā± 1.1X |
| Ā | 14 | 3.9 Ā± 0.7 | 5.1 Ā± 1.9 | 3.9 Ā± 0.7 | 4.6 Ā± 0.5 |
| Ā | 21 | 3.5 Ā± 1.0 | 4.0 Ā± 1.7 | 3.6 Ā± 1.0 | 3.8 Ā± 0.8 |