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Table 2 Medians and quartiles for the distribution of the pre-and postoperative WOMAC index and EuroQuol-5D utility index [%] in patients undergoing total knee arthroplasty, their respective intraindividual change [%] with p-values derived from sign tests, the resulting gain in patient quality of life [QALYs] and the marginal cost effectiveness ratio [€/QALY] from the health care insurers' perspective

From: Clinical benefit and cost effectiveness of total knee arthroplasty in the older patient

  Median Q1 -Q3 p(sign test)
WOMAC pre 41% 34 - 47%  
WOMAC post 81% 64 - 88%  
WOMAC change 38% 25 - 45% p < 0.001
EQ-5D pre 40% 32 - 54%  
EQ-5D post 70% 65 - 78%  
EQ-5D change 30% 15 - 40% p = 0.008
WOMAC based gain 4.59 QALYs 2.39 - 6.21 QALYs  
EQ-5D based gain 2.93 QALYs 1.75 - 5.59 QALYs  
WOMAC based 1795 1588 - 3288  
marginal costs €/QALY €/QALY  
EQ-5D based 3064 1613 - 5291  
marginal costs €/QALY €/QALY