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Table 1 Overview of baseline characteristics in the compared groups; SD = standard deviation, MSM = men who have sex with men, HPC = patients from countries of high HIV prevalence, ART = antiretroviral therapy, IQR = interquartile range, NNRTI = antiretroviral regimen based on NNRTI, PI = antiretroviral regimen based on PI, NRTI or NNRTI/PI = antiretroviral regimen either consisting of NRTI only or including NNRTI and PI; p-values calculated by T-test, Chi-squared or Mann-Whitney-U test

From: Impaired CD4-cell immune reconstitution upon HIV therapy in patients with toxoplasmic encephalitis compared to patients with pneumocystis pneumonia as AIDS indicating disease

 

TE (n = 61)

PCP (n = 196)

p

 

n/mean

%/SD

n/mean

%/SD

 

Age

40.8

8.4

41.0

10.5

0.876

Female

16

26.2%

28

14.3%

0.031

Migrant

13

21.3%

41

20.9%

0.948

Transmission risk

     

MSM

25

41.0%

114

58.2%

0.013

HPC

11

18.0%

14

7.1%

 

Other

25

41.0%

68

34.7%

 

ART initiation date

Apr 02 (median)

34 months (IQR)

Sep 01 (median)

35 months (IQR)

0.631

Firstline-ART

     

NNRTI

11

18.0%

34

17.3%

0.069

PI

45

73.8%

119

60.7%

 

NNRTI/PI

3

4.9%

37

18.9%

 

NRTI

2

3.3%

6

3.1%

 

Baseline values

     

CD4/μl

60.9

44.2

44.7

42.1

0.022

CD8/μl

637.2

301.2

726.4

492.3

0.222

%CD4

6.8

4.3

4.8

3.9

0.013

%CD8

67.0

13.3

65.2

15.9

0.565

VL (log10 Kop/ml)

4.46

1.20

5.00

1.02

0.008

Lymphocytes/μl

981.8

544.1

1,056.0

887.39

0.635