Table 2 Changes in baseline BP measurements for responders at the end of 4 weeks of therapy
Efficacy Parameters | Metoprolol XL + Chlorthalidone (n = 32) | Metoprolol XL + HCTZ (n = 32) | P value |
|---|---|---|---|
Mean SBP (mmHg) (At baseline) | 153.34 ± 8.61 (138.0-170.0) | 154.47 ± 11.94 (134.0-190.0) | 0.667 |
Mean SBP (mmHg) (At 4 weeks) | 126.31 ± 8.17 (110.0-138.0) | 128.16 ± 5.83 (112.0-138.0) | 0.303 |
Mean DBP (mmHg) (At baseline) | 96.25 ± 5.72 (80.0-108.0) | 96.18 ± 5.17 (90.0-104.0) | 0.964 |
Mean DBP(mmHg) (At 4 weeks) | 81.72 ± 6.24 (60.0-88.0) | 81.53 ± 4.51 (70.0-88.0) | 0.891 |
Mean Fall in SBP (mmHg) | -27.03 ± 8.31 | -26.31 ± 12.56 | 0.788 |
Mean Fall in DBP (mmHg) | -14.53 ± 6.73 | -14.66 ± 6.31 | 0.939 |